Evidence map›Paper›PMID 38828467›Full record

ArticleAdvanced functional materials2024

Exploring and Analyzing the Systemic Delivery Barriers for Nanoparticles.

Lin Wang, Skyler Quine, Alex N Frickenstein, Michael Lee, Wen Yang, Vinit M Sheth, Margaret D Bourlon, Yuxin He, Shanxin Lyu, Lucila Garcia-Contreras and 2 more

Abstract read
In one paragraph

Article in Advanced functional materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lin WangStephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA.
Skyler QuineStephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA.
Alex N FrickensteinStephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA.
Michael LeeStephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA.
Wen YangStephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA.
Vinit M ShethStephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA.
Margaret D BourlonCollege of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, 73117, USA.
Yuxin HeStephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA.
Shanxin LyuStephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA.
Lucila Garcia-ContrerasCollege of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, 73117, USA.
Yan D ZhaoDepartment of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, 73012, USA.
Stefan WilhelmStephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA.ORCID 0000-0003-2167-6221

Funding

Use of 3D Quantitative Optical Methods to Optimize Mebendazole Treatment of Ovarian CancerP20GM135009 · NIGMS · UNIVERSITY OF OKLAHOMA · PI Yuye Ling · 2022 to 2026
$13.6M
A novel framework for nanomedicine developmentR35GM150758 · NIGMS · UNIVERSITY OF OKLAHOMA · PI Stefan Wilhelm · 2023 to 2026
$1.5M
NIGMS NIH HHS P20 GM135009NIGMS NIH HHS R35 GM150758
6 · The paper itself

Abstract

Most nanomedicines require efficient

Indexed as

biodistributionbiological barriersliterature surveymononuclear phagocyte system (MPS)nano-bio interactionNanomedicinenanoparticle blood removal pathways (NBRP)nanoparticle deliverypharmacokineticsreticuloendothelial system (RES)

Identifiers

PMID38828467
PMCPMC11142462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.