Evidence map›Paper›PMID 38828389›Full record

ArticleFrontiers in aging neuroscience2024

Longitudinal assessment of plasma biomarkers for early detection of cognitive changes in subjective cognitive decline.

Cheng-Hao Hsieh, Chien-An Ko, Chih-Sung Liang, Po-Kuan Yeh, Chia-Kuang Tsai, Chia-Lin Tsai, Guan-Yu Lin, Yu-Kai Lin, Ming-Chen Tsai, Fu-Chi Yang

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cheng-Hao HsiehDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Chien-An KoDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Chih-Sung LiangDepartment of Psychiatry, Beitou Branch, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Po-Kuan YehDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Chia-Kuang TsaiDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Chia-Lin TsaiDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Guan-Yu LinDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Yu-Kai LinDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Ming-Chen TsaiDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Fu-Chi YangDepartment of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Individuals experiencing subjective cognitive decline (SCD) are at an increased risk of developing mild cognitive impairment and dementia. Early identification of SCD and neurodegenerative diseases using biomarkers may help clinical decision-making and improve prognosis. However, few cross-sectional and longitudinal studies have explored plasma biomarkers in individuals with SCD using immunomagnetic reduction. Objective: To identify plasma biomarkers for SCD. Methods: Fifty-two participants [38 with SCD, 14 healthy controls (HCs)] underwent baseline assessments, including measurements of plasma Aβ Results: Higher baseline plasma Aβ Conclusion: Baseline plasma Aβ

Indexed as

Alzheimer’s diseasebiomarkerscognitive declinedementianeurodegenerative diseasesplasma

Identifiers

PMID38828389
PMCPMC11140011

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.