Evidence map›Paper›PMID 38828323›Full record

ArticleHeliyon2024

SIAH2 is specifically expressed during cervical carcinogenesis, and closely relates to the abnormal proliferation of cervical epithelial cells.

Li-Ping Jing, Meng Li, Xi-Yan Xia, Xin Zheng, Jia-Yu Chen, Jing He, Xue-Wei Zhuang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Li-Ping JingClinical Laboratory Department, Liaoning Cancer Hospital & Institute, 110042, Shenyang, Liaoning, China.
Meng LiDepartment of Laboratory, Shandong Provincial Third Hospital, Shandong University, 250031, Jinan, Shandong, China.
Xi-Yan XiaDepartment of Immunology Teaching and Research, Jinan Vocational College of Nursing, 250102, Jinan, Shandong, China.
Xin ZhengDepartment of Laboratory, Shandong Provincial Third Hospital, Shandong University, 250031, Jinan, Shandong, China.
Jia-Yu ChenDepartment of Laboratory, Shandong Provincial Third Hospital, Shandong University, 250031, Jinan, Shandong, China.
Jing HeSecond Clinical Medical College, Shandong University of Traditional Chinese Medicine, 250014, Jinan, Shandong, China.
Xue-Wei ZhuangDepartment of Laboratory, Shandong Provincial Third Hospital, Shandong University, 250031, Jinan, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cervical cancer is one of the most common malignancies in women worldwide. As a RING type ubiquitin ligase, SIAH2 has been reported to promote the progression of a variety of tumors by interacting with and targeting multiple chaperones and substrates. The aim of this study was to further identify the role and the related molecular mechanisms involved of SIAH2 in cervical carcinogenesis. Methods and results: Cellular assays Conclusion: Targeting SIAH2 may be beneficial to the treatment of cervical cancer.

Indexed as

Cervical carcinogenesisCisplatin sensitivityGSK3βSIAH2Specific tissues expressionUbiquitin ligase

Identifiers

PMID38828323
PMCPMC11140618

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.