ArticleMalariaWorld journal2013
Asymptomatic malaria and intestinal helminth co-infection among children in a rural community in Southwest Nigeria.
Article in MalariaWorld journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
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Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence and effect of Plasmodium spp. and hookworm co-infection on malaria parasite density and haemoglobin level: a meta-analysis.Scientific reports · 2022Pooled it
- Plasmodium and intestinal parasite perturbations of the infected host's inflammatory responses: a systematic review.Parasites & vectors · 2018Pooled it
- Asymptomatic Malaria Infection and Hidden Parasitic Burden in Gabonese Schoolchildren: Unveiling Silent Co-Infections in Rural and Urban Settings.Tropical medicine and infectious disease · 2024Article
- Asymptomatic Malaria and Helminths Coinfection and Its Association with Anemia among Primary School Children in Gedeo Zone, Southern Ethiopia: A Cross-Sectional Study.Journal of tropical medicine · 2021Article
- Co-endemicity of Plasmodium falciparum and Intestinal Helminths Infection in School Age Children in Rural Communities of Kwara State Nigeria.PLoS neglected tropical diseases · 2015Article
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Authors and funding
3 authors.
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Abstract
Background: Malaria is prevalent in sub-Saharan Africa, where other concomitant parasitic infections, including intestinal helminths, are common. However, little is known about how concurrent infections affect the expression or pathogenesis of each other. This study aimed to document the prevalence rates of malaria and intestinal helminths individually and as co-infection among asymptomatic children in a rural community in southwest Nigeria. Materials and Methods: Apparently healthy children aged 1-17 years, who were enrolled into a larger study that evaluated the efficacy and safety of two anti-helminthic drugs, were evaluated for intestinal helminths by stool examination using the saline wet mount and Kato-Katz methods. Capillary blood from finger prick samples was used for haematocrit determination and malaria screening by microscopy. Data analysis was conducted using SPSS and significance levels were set at p < 0.05. Results: Eighty-nine of 178 (50%) enrolees were male. One hundred and fifteen of the 178 (64.6%) children had at least one intestinal helminthic infection while 69 (60%) thereof harboured multiple helminthic infections. Malaria parasites were encountered in 35/178 (19.7%) of the enrolees. Parasite density was ≤500/μl in 51.4% (18/35), 501-1,000/μl in 9 (25.7%) and 1,000-4,720/μl in 8 (22.9%) of the children. Malaria-helminth co-infection was detected in 24/115 (20.9%) of the children. The prevalence [60/115 (52.2%) versus 8/63 (12.7%) p<0.0001] and severity of anaemia were significantly higher among children with worms compared to those without worms. For mild anaemia this was 53/115 (46.8%; with worms) versus 7/63 (11.1%; no worms p<0.0001); for moderate anaemia 2/115 (1.74%; with worms) versus 1/63 (1.59%; without worms; p<0.271). Conclusion: Malaria and helminths co-infection is common among apparently asymptomatic children in the rural community studied. Co-infections increase the problems associated with anaemia and aggravate the burden of disease in Nigerian children.
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