Evidence map›Paper›PMID 38828099›Full record

Article3 Biotech2024

Diosgenin intervention: targeting lipophagy to counter high glucose diet-induced lipid accumulation and lifespan reduction.

Thiruppathi Govindhan, Mohankumar Amirthalingam, Shanmugam Govindan, Kalaiselvi Duraisamy, Jeong Hoon Cho, Shinkichi Tawata, Saravana Bhavan Periyakali, Sundararaj Palanisamy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thiruppathi Govindhan *Department of Zoology, Bharathiar University, Coimbatore, Tamil Nadu 641046 India.
Mohankumar Amirthalingam *PAK Research Center, University of the Ryukyus, Senbaru 1, Nishihara-Cho, Okinawa, 903-0213 Japan.
Shanmugam GovindanDepartment of Zoology, Bharathiar University, Coimbatore, Tamil Nadu 641046 India.
Kalaiselvi DuraisamyDepartment of Agricultural Chemistry, Institute of Environmentally Friendly Agriculture, College of Agriculture and Life Science, Chonnam National University, Gwangju, 61186 Republic of Korea.
Jeong Hoon ChoDepartment of Biology Education, College of Education, Chosun University, Gwangju, 61452 Republic of Korea.
Shinkichi TawataPAK Research Center, University of the Ryukyus, Senbaru 1, Nishihara-Cho, Okinawa, 903-0213 Japan.
Saravana Bhavan PeriyakaliDepartment of Zoology, Bharathiar University, Coimbatore, Tamil Nadu 641046 India.
Sundararaj PalanisamyDepartment of Zoology, Bharathiar University, Coimbatore, Tamil Nadu 641046 India.ORCID 0000-0001-9927-5538

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Diosgenin (DG), a well-known steroidal sapogenin, is abundantly found in the plants of the Dioscoreaceae family and exhibits diverse pharmacological properties. In our previous study, we demonstrated that DG supplementation protected Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-024-04017-3.

Indexed as

Anti-obesityC. elegansDiosgeninFat metabolismLipophagySteroidal sapogenin

Identifiers

PMID38828099
PMCPMC11143156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.