Evidence map›Paper›PMID 38828026›Full record

Trial reportDrug design, development and therapy2024

Influences of Propofol, Ciprofol and Remimazolam on Dreaming During Anesthesia for Gastrointestinal Endoscopy: A Randomized Double-Blind Parallel-Design Trial.

Rui Zhou, Lijuan Fu, Shu Liu, Sanjie Gao, Zhifu Zhao, Wencai Jiang, Li Liu, Weiqiao Ren, Dongmei Xiang, Xing You and 11 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug design, development and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  7. Comparison of Ciprofol-Nalbuphine and Propofol-Nalbuphine Sedation During Painless Gastrointestinal Endoscopy: A Randomized Controlled Trial.Medical science monitor : international medical journal of experimental and clinical research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Rui Zhou *Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Translational Research Institute of Brain and Brain-Like Intelligence, Clinical Research Center for Anesthesiology and Perioperative Medicine, Department of Anesthesiology and Perioperative Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, 200434, People's Republic of China.ORCID 0000-0002-1479-4409
Lijuan Fu *Department of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Shu Liu *Department of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Sanjie GaoDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Zhifu ZhaoDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Wencai JiangDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Li LiuDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Weiqiao RenDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Dongmei XiangDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Xing YouDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Chunyong TangDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Yukai ZhouDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Yanqing SongDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Juan XieDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Li XieDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Ru YuDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Xianjie ZhangDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.ORCID 0000-0002-8870-711X
Dan ZhouDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Jia HanDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Leqiang XiaDepartment of Anesthesiology, Deyang People's Hospital, Deyang, 618000, People's Republic of China.
Lize XiongShanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Translational Research Institute of Brain and Brain-Like Intelligence, Clinical Research Center for Anesthesiology and Perioperative Medicine, Department of Anesthesiology and Perioperative Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, 200434, People's Republic of China.ORCID 0000-0002-9204-8129

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To compare the influences of propofol, ciprofol and remimazolam on dreaming during painless gastrointestinal endoscopy. Methods: This study was a single-center, prospective, parallel-design, double-blind, randomized clinical trial. Between May 2023 and October 2023, patients undergoing elective painless gastrointestinal endoscopy were recruited and randomly allocated into one of the three groups. Demographic data, intraoperative information, incidence of dreaming, insufficient anesthesia and intraoperative awareness, type of dream, patient satisfaction score, adverse events, and improvement of sleep quality were collected. Results: The difference in incidence of dreaming among the three groups was not significant (33.33% vs 48.33% vs 41.67%, Conclusion: Anesthesia with propofol, ciprofol and remimazolam, respectively, for gastrointestinal endoscopy did not induce statistical difference in the incidence of dreaming, despite that all of them are more likely to induce pleasant dreams.

Indexed as

DreamsEndoscopy, GastrointestinalPropofolAdultAgedAnesthesiaAnesthetics, IntravenousBenzodiazepinesDouble-Blind MethodFemaleHumansMaleMiddle AgedProspective StudiesAnesthetics, IntravenousBenzodiazepinesPropofolremimazolamciprofoldreamingendoscopic sedationpropofolremimazolam

Identifiers

PMID38828026
PMCPMC11144431

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.