Evidence map›Paper›PMID 38827661›Full record

ArticleJournal of family medicine and primary care2024

Non-invasive predictors to grade esophageal varices in liver cirrhosis patients.

Sushma S Rapelly, Shraddha Singh, Narsingh Verma, Sandeep Bhattacharya, Sumit Rungta

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Article in Journal of family medicine and primary care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Sushma S RapellyDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Shraddha SinghDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Narsingh VermaDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Sandeep BhattacharyaDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Sumit RungtaDepartment of Medical Gastroenterology, King George's Medical University, Lucknow, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Portal hypertension commonly occurs due to liver cirrhosis, and esophageal varices (EV) is one of the major complications associated with it. The most common cause of death in liver cirrhosis is EV bleeding. Hence, GE screening for EV is required, which is an invasive procedure. Regular use of endoscopy results in low compliance due to cost and discomfort for patients. Hence, identifying non-invasive markers that could grade EV provides a useful screening tool for family physicians and primary health centers (PHCs) by referring the patient to higher centers for definitive treatment, which could reduce mortality due to variceal bleeding in cirrhotic patients. Aims: To assess non-invasive predictors of grade EV in patients diagnosed with liver cirrhosis. Settings and Design: Cross-sectional study. Methods and Material: A total of 109 patients with liver cirrhosis underwent clinical and biochemical evaluation, USG abdomen with spleen bipolar diameter, ascitic fluid analysis, and upper GE with a grade of EV are recorded. Statistical Analysis Used: SPSS software with Student Results: Aminotransferase to Platelet count Ratio Index (APRI) score >1.815, PC/SD ≤909, and SAAG >1.1g/dl showed EV in liver cirrhosis ( Conclusions: APRI score may be used in PHC as an early intervention to grade EV and refer the patient to higher centers for definitive treatment. This would prevent the progression of varices to rupture and reduce mortality due to variceal bleeds in liver cirrhosis patients.

Indexed as

APRIAspartate aminotransferase to platelet count ratio indexesophageal varicesEVgastro-endoscopyGEPC/SDPHCplatelet count to spleen diameter ratioprimary health centerreceiver operator characteristicROCSAAGserum ascites to albumin gradient

Identifiers

PMID38827661
PMCPMC11141952

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