ReviewFrontiers in cell and developmental biology2024
Vitrification of human blastocysts for couples undergoing assisted reproduction: an updated review.
Review in Frontiers in cell and developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07556601 (Clinical Validation of Ultra-rapid Blastocyst Vitrification), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Validation of Ultra-rapid Blastocyst Vitrification: a Randomized Pilot Study in Oocyte Donation Cycles
Who cites it
15 citing papers in PubMed.
- Bezafibrate and Cholic Acid-Mediated Lipid Reduction Improves the Cryotolerance of Vitrified In Vivo-Derived Porcine Embryos.Animals : an open access journal from MDPI · 2026Article
- Extended embryo culture and cumulative live birth in patients with limited embryos.Journal of assisted reproduction and genetics · 2026Article
- Transfer of fresh versus frozen embryos among underweight women: significant difference in the occurrence of small-for-gestational-age infants.Journal of assisted reproduction and genetics · 2026Article
- Progesterone-induced endometrial thickness changes do not affect singleton neonatal outcomes in frozen embryo transfer: a retrospective analysis of 6,331 newborns.BMC pregnancy and childbirth · 2026Article
- Register and biobank on influence of assisted reproduction on pregnancy, maternal and neonatal outcome : A prospective multicenter medical data register and biobank.Wiener klinische Wochenschrift · 2026Article
- A one-step short rehydration protocol for warming is associated with live birth outcomes in frozen blastocyst transfers: a retrospective cohort study.Reproductive biology and endocrinology : RB&E · 2026Article
- Reactive Oxygen Species in Embryo Development: Sources, Impacts, and Implications for In Vitro Culture Systems.Life (Basel, Switzerland) · 2026Review
- Research progress on novel bionic cryoprotectants in gamete and embryo cryopreservation.Frontiers in veterinary science · 2026Review
- Cryopreservation duration does not affect pregnancy or neonatal outcomes in single high-quality blastocyst transfers: a multicenter retrospective study.Frontiers in endocrinology · 2026Article
- Repeated cryopreservation is associated with poor pregnancy outcomes after frozen-thawed embryo transfer in women aged < 35 years: a propensity-score matched cohort study.European journal of medical research · 2025Article
- Crosstalk between H3K4me3 and oxidative stress is a potential target for the improvement of ART-derived embryos.Nature communications · 2025Article
- The impact of completely shrunken blastocysts on clinical outcomes in vitrified-warmed single blastocyst transfer cycles.Scientific reports · 2025Article
- Pregnancy Outcomes of Frozen-Thawed Blastocysts versus Blastocysts Derived from Frozen-Thawed Cleavage Embryos: A Retrospective Study.International journal of fertility & sterility · 2025Article
- Morphometric Blastocyst Assessment: A Retrospective Study Examining the Relationship Between Blastocyst Diameter and Area and Pregnancy Outcomes in Assisted Reproduction Technology Cycles.Journal of clinical medicine · 2025Article
- How adaptive solutions from marine mammal life history could address pressing problems in reproductive biomedicine.F&S reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past 40 years there has been a worldwide critical change in the field of assisted reproduction technology (ART), leading to the increased application of single blastocyst transfer, which is extremely important to avoid the risks of multiple pregnancy and associated complications for both mother and babies. Indeed, advancements in ART over the last few decades have been obtained thanks to several improvements, including ovarian stimulation, embryo culture conditions and, of course, progress in cryopreservation methods, especially with the application of vitrification. The ability to cryopreserve human embryos has improved significantly with vitrification compared to the initially adopted slow-freezing procedures. Since the introduction of vitrification, it has become the gold standard method to effectively cryopreserve human blastocysts. However, some new protocols are now being explored, such as the short warming procedure and even shorter exposure to the equilibration solution before vitrification, which seem to provide optimal results. Therefore, the main aim of the current narrative review, will be to illustrate the benefit of vitrification as an effective method to cryopreserve the human blastocyst and to illustrate new protocols and variations which in future may increase the performance of vitrification protocols.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.