Evidence map›Paper›PMID 38827380›Full record

ArticlePulmonary circulation2024

Assessing quality of life in pulmonary arterial hypertension: An independent prognostic marker.

Glenn Edward Malcolm Reeves, Julie Shepherd, Nicholas John Collins, Scott Twaddell, Rajinder Harjit Singh

Abstract read
In one paragraph

Article in Pulmonary circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Glenn Edward Malcolm ReevesJohn Hunter Hospital, NSW Health HNELHD, Hunter Regional Mail Centre Warabrook New South Wales Australia.ORCID 0000-0003-0776-8867
Julie ShepherdImmune & Clinical Trials Unit, John Hunter Hospital Newcastle New South Wales Australia.
Nicholas John CollinsJohn Hunter Hospital, NSW Health HNELHD, Hunter Regional Mail Centre Warabrook New South Wales Australia.ORCID 0000-0003-4722-0214
Scott TwaddellJohn Hunter Hospital, NSW Health HNELHD, Hunter Regional Mail Centre Warabrook New South Wales Australia.
Rajinder Harjit SinghJohn Hunter Hospital, NSW Health HNELHD, Hunter Regional Mail Centre Warabrook New South Wales Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary arterial hypertension (PAH, or PH Group 1), a disease of aberrant pulmonary vascular remodeling, causing progressive right heart failure (RHF) due to elevation of pulmonary vascular resistance (PVR). Patient mortality risk stratification guides choice and intensity of pharmacological intervention and is assessed by haemodynamics (especially PVR) as well as noninvasive tools including WHO functional class (FC), 6-min walk distance (6MWD), and NT-proBNP levels. Quality of life (QOL) assessment is acknowledged as a central aspect of patient-centered care, but our study sought to extend QOL's role as an additional noninvasive risk marker that could further refine risk stratification and hence therapeutic choices within a "treatment to target" paradigm (aiming to achieve low-risk status). This study found that QOL assessment using the PAH-SYMPACT© physical activity tool provided enhanced, independent mortality risk information, with one unit rise in this score associated with a 41% increase in likelihood risk (odds ratio 1.41, 95% confidence interval: 1.01-1.98 (

Indexed as

functional ability/impairment/quality of life/physical activityhealth outcomes assessment/cost effectivenessmortalityprognosispulmonary arterial hypertension

Identifiers

PMID38827380
PMCPMC11144421

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.