Evidence map›Paper›PMID 38827360›Full record

ArticleLonghua Chinese medicine2023

Associations between traditional Chinese medicine body constitution and obesity risk among US adults.

Xiangzhu Zhu, Xiaolin Yin, Xinqing Deng, Yevheniy Eugene Shubin, Harvey J Murff, Reid M Ness, Chang Yu, Martha J Shrubsole, Qi Dai

Abstract read
In one paragraph

Article in Longhua Chinese medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiangzhu ZhuDivision of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-4462-8815
Xiaolin YinShanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xinqing DengDepartment of Medicine, Vanderbilt University School of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Yevheniy Eugene ShubinSaint Joseph Health System, South Bend, IN, USA.
Harvey J MurffDepartment of Medicine, Division of Geriatric Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Reid M NessDepartment of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, Vanderbilt University Medical Center, Nashville, TN, USA.
Chang YuDepartment of Population Health, Division of Biostatistics, NYU Grossman School of Medicine, New York, NY, USA.
Martha J ShrubsoleDivision of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.
Qi DaiDivision of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ben Ho Park · 1995 to 2026
$172.8M
VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Calcium: magnesium balance, microbiota, and necroptosis and inflammationR01DK110166 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DAI, QI, SHRUBSOLE, MARTHA J. · 2017 to 2021
$3.4M
Methylomic biomarkers for magnesium deficiency and colon neoplasia preventionR01CA202936 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DAI, QI, HOU, LIFANG · 2016 to 2019
$2.5M
Personalized Prevention of Colorectal CancerR01CA149633 · NCI · VANDERBILT UNIVERSITY · PI DAI, QI, YU, CHANG · 2010 to 2014
$2.0M
Effect of magnesium treatment on vitamin D resistanceR03CA189455 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHRUBSOLE, MARTHA J. · 2014 to 2015
$167k
NCATS NIH HHS UL1 TR000445NCI NIH HHS P30 CA068485NCI NIH HHS R01 CA149633NCI NIH HHS R01 CA202936NCI NIH HHS R03 CA189455NCRR NIH HHS UL1 RR024975NIDDK NIH HHS R01 DK110166
6 · The paper itself

Abstract

Background: Traditional Chinese medicine (TCM) body constitution (BC), primarily determined by physiological and clinical characteristics, is an important process for clinical diagnosis and treatment and play a critical role in precision medicine in TCM. The purpose of the study was to explore whether the distributions of BC types differed by obesity status. Methods: We conducted a study to evaluate BC type in US population during 2012-2016. A total of 191 White participants from Personalized Prevention of Colorectal Cancer Trial (PPCCT) completed a self-administered Traditional Chinese Medicine Questionnaire (TCMQ, English version). In this study, we further compared the distribution of major types of TCM BC in the PPCCT to those Chinese populations stratified by obesity status. Results: We found the Blood-stasis frequency was higher in US White adults, 22.6% for individuals with BMI <30 and 11.2% for obese individuals, compared to 1.4% and 1.8%, respectively, in Chinese populations. We also found the percentages Inherited-special and Qi-stagnation were higher in US White adults than those in Chinese populations regardless of obesity status. However, the proportions of Yang-deficiency were higher in Chinese populations than those in our study conducted in US White adults regardless of obesity status. Conclusions: These new findings indicate the difference in distribution of BC types we observed between US and Chinese populations cannot be explained by the differences in prevalence of obesity. Further studies are needed to confirm our findings and understand the potential mechanism including genetic background and/or environmental factors.

Indexed as

body constitution (BC)obesityoverweightTraditional Chinese medicine (TCM)

Identifiers

PMID38827360
PMCPMC11142465

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.