Evidence map›Paper›PMID 38827339›Full record

ArticleIranian journal of biotechnology2024

Efficient Induction of Apoptosis in Lung Cancer Cells Using Bismuth Sulfide Nanoparticles.

Leila Nasehi, Hamed Rezaeejam, Hossein Danafar, Parvin Mirzaghavami, Ali Mohammadi, Mahda Delshad, Massoud Vosough

Abstract read
In one paragraph

Article in Iranian journal of biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Leila NasehiCancer Gene Therapy Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
Hamed RezaeejamDepartment of Radiology, School paramedical Sciences, Zanjan University of Medical Sciences, Zanjan, Iran.
Hossein DanafarZanjan pharmaceutical Biotechnology Research center, Zanjan University of Medical Sciences, Zanjan, Iran.
Parvin MirzaghavamiDepartment of Radiology, School paramedical Sciences, Zanjan University of Medical Sciences, Zanjan, Iran.
Ali MohammadiZanjan pharmaceutical Biotechnology Research center, Zanjan University of Medical Sciences, Zanjan, Iran.
Mahda DelshadDepartment of Medical Laboratory, School paramedical Sciences, Zanjan University of Medical Sciences, Zanjan, Iran.
Massoud VosoughDepartment of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The use of nanomaterial-based radiosensitizers to improve the therapeutic ratio has gained attraction in radiotherapy. Increased radiotoxicity applied to the tumor region may result in adverse impact on the unexposed normal cells to the radiation, a phenomenon known as radiation-induced bystander effect (RIBE). Objectives: This study aimed to investigate the effect of Bi Materials and Methods: Lung carcinoma epithelial cells were exposed to 6 MV x-ray photons at different doses of 2 and 8 Gy, with and without Bi Results: This study showed that ICCM collected from 2-Gy-irradiated A549 cells in the presence of Bi Conclusion: The results indicated that the presence of NPs did not affect bystander response enhancement at higher concentrations. These findings highlighted the potential use of radiation-enhancing agents and their benefits in radiotherapy techniques with high doses per fraction.

Indexed as

Bismuth NanoparticlesBystander EffectLung cancerRadiation Therapy

Identifiers

PMID38827339
PMCPMC11139445

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.