Evidence map›Paper›PMID 38827185›Full record

ArticleDEN open2025

Efficacy and safety of uncovered self-expandable metal stents for distal malignant biliary obstruction in unresectable non-pancreatic cancer.

Fumitaka Niiya, Naoki Tamai, Masataka Yamawaki, Jun Noda, Tetsushi Azami, Yuichi Takano, Fumiya Nishimoto, Masatsugu Nagahama

Abstract read
In one paragraph

Article in DEN open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fumitaka NiiyaDepartment of Internal Medicine Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.ORCID https://orcid.org/0000-0002-2248-8655
Naoki TamaiDepartment of Internal Medicine Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.
Masataka YamawakiDepartment of Internal Medicine Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.
Jun NodaDepartment of Internal Medicine Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.
Tetsushi AzamiDepartment of Internal Medicine Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.
Yuichi TakanoDepartment of Internal Medicine Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.ORCID https://orcid.org/0000-0001-6803-9460
Fumiya NishimotoDepartment of Internal Medicine Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.
Masatsugu NagahamaDepartment of Internal Medicine Division of Gastroenterology Showa University Fujigaoka Hospital Kanagawa Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The efficacy of uncovered self-expandable metal stents (UCSEMS) versus fully covered self-expandable metal stents for distal malignant biliary obstruction remains controversial. Additionally, the heterogeneity of the disease conditions has been indicated in previous studies because pancreatic and non-pancreatic cancers have different characteristics in clinical course. Therefore, the etiology of biliary obstruction necessitates investigations stratified by primary disease. This study aimed to evaluate the outcomes of UCSEMS, specifically for non-pancreatic cancer-induced distal malignant biliary obstruction. Methods: We conducted a single-center retrospective review to evaluate the time to recurrent biliary obstruction and frequency of adverse events (AEs) in patients receiving UCSEMS for unresectable non-pancreatic cancer-induced malignant biliary obstruction. Results: Overall, 32 patients were enrolled in the study between January 2016 and December 2023. The median time to recurrent biliary obstruction was 140 days. AE rates were low at 3.1% for both pancreatitis and cholecystitis, suggesting a potential benefit of UCSEMS in reducing post-procedural AEs. Conclusion: UCSEMS may reduce the risk of post-procedural AEs and should be considered in patients at high risk of post-endoscopic retrograde cholangiopancreatography pancreatitis. However, the patency period may be shorter, necessitating future comparative research with fully covered self-expandable metal stents to determine the optimal stent choice.

Indexed as

biliarydistalobstructionsafetyself‐expandable metallic stent

Identifiers

PMID38827185
PMCPMC11143304

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.