Evidence map›Paper›PMID 38827172›Full record

ArticleBioactive materials2024

Reprogramming exosomes for immunity-remodeled photodynamic therapy against non-small cell lung cancer.

Jiao Guo, Wei Zhao, Xinyu Xiao, Shanshan Liu, Liang Liu, La Zhang, Lu Li, Zhenghang Li, Zhi Li, Mengxia Xu and 4 more

Abstract read
In one paragraph

Article in Bioactive materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
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  11. 80 years of extracellular vesicles: from discovery to clinical translation.Extracellular vesicles and circulating nucleic acids · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jiao GuoSchool of Basic Medical Science, Chongqing Medical University, Chongqing, 400016, China.
Wei ZhaoSchool of Basic Medical Science, Chongqing Medical University, Chongqing, 400016, China.
Xinyu XiaoSchool of Basic Medical Science, Chongqing Medical University, Chongqing, 400016, China.
Shanshan LiuDepartment of Plastic and Maxillofacial Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Liang LiuSchool of Basic Medical Science, Chongqing Medical University, Chongqing, 400016, China.
La ZhangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Lu LiSchool of Basic Medical Science, Chongqing Medical University, Chongqing, 400016, China.
Zhenghang LiDepartment of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Zhi LiTraditional Chinese Medicine Hospital of Bijie City, Guizhou province, 551700, China.
Mengxia XuTraditional Chinese Medicine Hospital of Bijie City, Guizhou province, 551700, China.
Qiling PengSchool of Basic Medical Science, Chongqing Medical University, Chongqing, 400016, China.
Jianwei WangSchool of Basic Medical Science, Chongqing Medical University, Chongqing, 400016, China.
Yuxian WeiDepartment of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Ning JiangDepartment of Pathology, School of Basic Medical Science, Chongqing Medical University, Chongqing, 400016, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional treatments against advanced non-small cell lung cancer (NSCLC) with high morbidity and mortality continue to be dissatisfactory. Given this situation, there is an urgent requirement for alternative modalities that provide lower invasiveness, superior clinical effectiveness, and minimal adverse effects. The combination of photodynamic therapy (PDT) and immunotherapy gradually become a promising approach for high-grade malignant NSCLC. Nevertheless, owing to the absence of precise drug delivery techniques as well as the hypoxic and immunosuppressive characteristics of the tumor microenvironment (TME), the efficacy of this combination therapy approach is less than ideal. In this study, we construct a novel nanoplatform that indocyanine green (ICG), a photosensitizer, loads into hollow manganese dioxide (MnO

Indexed as

ImmunotherapyNon-small cell lung cancerPD-L1PDTTargeted deliveryTumor microenvironment

Identifiers

PMID38827172
PMCPMC11141154

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.