Evidence map›Paper›PMID 38826931›Full record

ArticleCureus2024

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) in a 25-Year-Old Patient: A Case Report.

Zahid Ullah, Ebad-Ur Rehman Syed, Noman Salih, Yamna Ali, Abdul Wahab, Hidayat Ullah

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zahid UllahGeneral Medicine, Khyber Teaching Hospital, Peshawar, PAK.
Ebad-Ur Rehman SyedInternal Medicine, Royal College of Surgeons in Ireland, Busaiteen, BHR.
Noman SalihInternal Medicine, Hayatabad Medical Complex Peshawar, Peshawar, PAK.
Yamna AliInternal Medicine, Hayatabad Medical Complex Peshawar, Peshawar, PAK.
Abdul WahabInternal Medicine, Hayatabad Medical Complex Peshawar, Peshawar, PAK.
Hidayat UllahMedical C Unit, Hayatabad Medical Complex Peshawar, Peshawar, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare genetic disorder caused by mutations in the NOTCH3 gene, resulting in subcortical infarctions and leukoencephalopathy. It predominantly affects the brain's small blood arteries, resulting in repeated ischemic episodes including transient ischemic attacks and strokes leading to cognitive impairment and mental symptoms. We provide a case study of a 25-year-old patient suspected of having meningoencephalitis. CADASIL was diagnosed based on clinical examination, imaging investigations, and genetic analysis. Optimal patient care for this complicated illness requires early detection and proper management.

Indexed as

cadasilcognitive declinehereditaryischemic eventsnotch3 genepsychiatric symptoms

Identifiers

PMID38826931
PMCPMC11144273

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.