Evidence map›Paper›PMID 38826908›Full record

ArticleCureus2024

Advancing Prostate Cancer Staging: A Single-Step Approach With Bi-parametric and Whole-Body Diffusion MRI in an African Cohort.

George Asafu Adjaye Frimpong, Evans Aboagye, Emmanuel Asante, Kwaku Addai A Appiah, Osei Owusu-Afriyie, Adwoa O Asare, Dorcas Atuobi, Bernard D Akpaloo, Bright Antwi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

George Asafu Adjaye FrimpongRadiology, Kwame Nkrumah University of Science and Technology, Kumasi, GHA.
Evans AboagyeResearch and Development, Spectra Health Imaging and Interventional Radiology, Kumasi, GHA.
Emmanuel AsanteResearch and Development, Spectra Health Imaging and Interventional Radiology, Kumasi, GHA.
Kwaku Addai A AppiahSurgery, Kwame Nkrumah University of Science and Technology, Kumasi, GHA.
Osei Owusu-AfriyiePathology, Kwame Nkrumah University of Science and Technology, Kumasi, GHA.
Adwoa O AsareOncology, Komfo Anokye Teaching Hospital, Kumasi, GHA.
Dorcas AtuobiRadiology, Spectra Health Imaging and Interventional Radiology, Kumasi, GHA.
Bernard D AkpalooRadiology, Spectra Health Imaging and Interventional Radiology, Kumasi, GHA.
Bright AntwiRadiology, Spectra Health Imaging and Interventional Radiology, Kumasi, GHA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo document our initial experience using whole-body diffusion-weighted magnetic resonance imaging (WB-DWI/MRI) and bi-parametric magnetic resonance imaging (bpMRI) as a single exam in the staging of biopsy-proven prostate cancers.

methodsThis retrospective study involved 120 African men with biopsy-confirmed prostate cancer (PCa). All the participants had a single exam that included both a bpMRI and a WB-DWI/MRI. The results were analyzed based on the American Urological Association's risk stratification system and evaluated using descriptive statistics.

resultsThe combined imaging approach confirmed PCa in all cases, identifying pelvic lymph node metastases in 21 (17.5%) patients. Among 72 high-risk patients, bpMRI+WB-DWI/MRI detected pelvic lymph node metastases in 18 (25.0%), bone metastases in 15 (20.8%), retroperitoneal lymph node metastases in six (8.3%), and extraprostatic extension in 18 (25%), with no solid organ metastases observed.

conclusionThe combination of WB-DWI/MRI and bpMRI in a single-step approach demonstrates diagnostic potential in primary prostate cancer staging for high-risk groups, with the added advantage of shorter examination times, lower patients' costs, and elimination of the risks of adverse events associated with the use of contrast agents and exposure to radiation.

Indexed as

african menbiparametric mriprostate cancerstagingwhole-body diffusion-weighted mri

Identifiers

PMID38826908
PMCPMC11142458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.