Evidence map›Paper›PMID 38826780›Full record

ReviewFrontiers in oncology2024

MicroRNAs and angiosarcoma: are there promising reports?

Amir Modarresi Chahardehi, Arya Afrooghe, Nikoo Emtiazi, Sajjad Rafiei, Negin Jafarkhanloo Rezaei, Sarvin Dahmardeh, Fatemeh Farz, Zahra Naderi, Reza Arefnezhad, Hossein Motedayyen

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amir Modarresi ChahardehiKimia Andisheh Teb Medical and Molecular Research Laboratory Co., Tehran, Iran.
Arya AfroogheSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Nikoo EmtiaziDepartment of Pathology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
Sajjad RafieiMedical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran.
Negin Jafarkhanloo RezaeiSchool of Medicine, Najafabad University of Medical Sciences, Isfahan, Iran.
Sarvin DahmardehFaculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Fatemeh FarzStudent Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Zahra NaderiStudent Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Reza ArefnezhadCoenzyme R Research Institute, Tehran, Iran.
Hossein MotedayyenAutoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, microRNAs (miRNAs) have garnered increasing attention for their potential implications in cancer pathogenesis, functioning either as oncogenes or tumor suppressors. Notably, angiosarcoma, along with various other cardiovascular tumors such as lipomas, rhabdomyomas, hemangiomas, and myxomas, has shown variations in the expression of specific miRNA subtypes. A substantial body of evidence underscores the pivotal involvement of miRNAs in the genesis of angiosarcoma and certain cardiovascular tumors. This review aims to delve into the current literature on miRNAs and their prospective applications in cardiovascular malignancies, with a specific focus on angiosarcoma. It comprehensively covers diagnostic methods, prognostic evaluations, and potential treatments while providing a recapitulation of angiosarcoma's risk factors and molecular pathogenesis, with an emphasis on the role of miRNAs. These insights can serve as the groundwork for designing randomized control trials, ultimately facilitating the translation of these findings into clinical applications. Moving forward, it is imperative for studies to thoroughly scrutinize the advantages and disadvantages of miRNAs compared to current diagnostic and prognostic approaches in angiosarcoma and other cardiovascular tumors. Closing these knowledge gaps will be crucial for harnessing the full potential of miRNAs in the realm of angiosarcoma and cardiovascular tumor research.

Indexed as

angiosarcomacancercardiovascular tumormicroRNAoncogenesistumor suppressor

Identifiers

PMID38826780
PMCPMC11143796

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.