Evidence map›Paper›PMID 38826698›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2024

Aerodynamic Simulation of Small Airway Resistance: A New Imaging Biomarker for Chronic Obstructive Pulmonary Disease.

Di Zhang, Yu Guan, Xiuxiu Zhou, Mingzi Zhang, Yu Pu, Pengchen Gu, Yi Xia, Yang Lu, Jia Chen, Wenting Tu and 8 more

Abstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Small Airway Disease in Pre-COPD and Early COPD: Insights Into the Pulmonary "Silent Zone".International journal of chronic obstructive pulmonary disease · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Di Zhang *Department of Radiology, Second Affiliated Hospital, Naval Medical University, Shanghai, People's Republic of China.
Yu Guan *Department of Radiology, Second Affiliated Hospital, Naval Medical University, Shanghai, People's Republic of China.ORCID 0000-0001-9416-058X
Xiuxiu ZhouDepartment of Radiology, Second Affiliated Hospital, Naval Medical University, Shanghai, People's Republic of China.
Mingzi ZhangScientific Research Department, Shanghai Aitrox Technology Corporation Limited, Shanghai, People's Republic of China.
Yu PuDepartment of Radiology, Second Affiliated Hospital, Naval Medical University, Shanghai, People's Republic of China.
Pengchen GuScientific Research Department, Shanghai Aitrox Technology Corporation Limited, Shanghai, People's Republic of China.
Yi XiaDepartment of Radiology, Second Affiliated Hospital, Naval Medical University, Shanghai, People's Republic of China.
Yang LuScientific Research Department, Shanghai Aitrox Technology Corporation Limited, Shanghai, People's Republic of China.
Jia ChenScientific Research Department, Shanghai Aitrox Technology Corporation Limited, Shanghai, People's Republic of China.
Wenting TuDepartment of Radiology, Second Affiliated Hospital, Naval Medical University, Shanghai, People's Republic of China.ORCID 0000-0003-1010-7189
Kunyao HuangScientific Research Department, Shanghai Aitrox Technology Corporation Limited, Shanghai, People's Republic of China.
Jixin HouScientific Research Department, Shanghai Aitrox Technology Corporation Limited, Shanghai, People's Republic of China.
Hua YangScientific Research Department, Shanghai Aitrox Technology Corporation Limited, Shanghai, People's Republic of China.
Chicheng FuScientific Research Department, Shanghai Aitrox Technology Corporation Limited, Shanghai, People's Republic of China.
Qu FangScientific Research Department, Shanghai Aitrox Technology Corporation Limited, Shanghai, People's Republic of China.
Chuan HeScientific Research Department, Shanghai Aitrox Technology Corporation Limited, Shanghai, People's Republic of China.
Shiyuan LiuDepartment of Radiology, Second Affiliated Hospital, Naval Medical University, Shanghai, People's Republic of China.ORCID 0000-0003-3420-0310
Li FanDepartment of Radiology, Second Affiliated Hospital, Naval Medical University, Shanghai, People's Republic of China.ORCID 0000-0003-4722-3933

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To develop a novel method for calculating small airway resistance using computational fluid dynamics (CFD) based on CT data and evaluate its value to identify COPD. Patients and Methods: 24 subjects who underwent chest CT scans and pulmonary function tests between August 2020 and December 2020 were enrolled retrospectively. Subjects were divided into three groups: normal (10), high-risk (6), and COPD (8). The airway from the trachea down to the sixth generation of bronchioles was reconstructed by a 3D slicer. The small airway resistance (R Results: The R Conclusion: Airway CFD is a valuable method for estimating the small airway resistance, where the derived R

Indexed as

Airway ResistanceHydrodynamicsLungPredictive Value of TestsPulmonary Disease, Chronic ObstructiveTomography, X-Ray ComputedAgedComputer SimulationFemaleForced Expiratory VolumeHumansMaleMiddle AgedRadiographic Image Interpretation, Computer-AssistedRespiratory Function TestsRetrospective StudiesCOPDCTfluid dynamicssmall airway disease

Identifiers

PMID38826698
PMCPMC11141759

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.