Evidence map›Paper›PMID 38826656›Full record

ArticleCognitive neurodynamics2024

Complexity decline of hippocampal CA1 circuit model due to cholinergic deficiency associated with Alzheimer's disease.

YeZi Li, XiaoLi Yang, SiLu Yan, ZhongKui Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cognitive neurodynamics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

YeZi LiSchool of Mathematics and Statistics, Shaanxi Normal University, Xi'an, 710062 People's Republic of China.
XiaoLi YangSchool of Mathematics and Statistics, Shaanxi Normal University, Xi'an, 710062 People's Republic of China.
SiLu YanSchool of Mathematics and Statistics, Shaanxi Normal University, Xi'an, 710062 People's Republic of China.
ZhongKui SunSchool of Mathematics and Statistics, Northwestern Polytechnical University, Xi'an, 710072 People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A hallmark of Alzheimer's disease (AD) is cholinergic system dysfunction, directly affecting the hippocampal neurons. Previous experiments have demonstrated that reduced complexity is one significant effect of AD on electroencephalography (EEG). Motivated by these, this study explores reduced EEG complexity of cholinergic deficiency in AD by neurocomputation. We first construct a new hippocampal CA1 circuit model with cholinergic action. M-current

Indexed as

Alzheimer’s diseaseAutomatic mutual informationCholinergic deficiencyDynamical analysisHippocampal CA1 neuronsSample entropy

Identifiers

PMID38826656
PMCPMC11143170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.