Evidence map›Paper›PMID 38826646›Full record

ArticleCognitive neurodynamics2024

Neurophysiological and other features of working memory in older adults at risk for dementia.

Rachel A Patterson, Heather Brooks, Mina Mirjalili, Neda Rashidi-Ranjbar, Reza Zomorrodi, Daniel M Blumberger, Corinne E Fischer, Alastair J Flint, Ariel Graff-Guerrero, Nathan Herrmann and 10 more

Abstract read
In one paragraph

Article in Cognitive neurodynamics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Rachel A PattersonCentre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.ORCID 0000-0003-0131-4178
Heather BrooksCentre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.
Mina MirjaliliCentre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.
Neda Rashidi-RanjbarCentre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.
Reza ZomorrodiCentre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.ORCID 0000-0002-1648-843X
Daniel M Blumberger *Centre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.
Corinne E Fischer *Department of Psychiatry, TemertyFaculty of Medicine, University of Toronto, Toronto, ON M5S 1A1 Canada.ORCID 0000-0002-1047-0167
Alastair J Flint *Department of Psychiatry, TemertyFaculty of Medicine, University of Toronto, Toronto, ON M5S 1A1 Canada.
Ariel Graff-Guerrero *Centre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.ORCID 0000-0001-9301-2171
Nathan Herrmann *Department of Psychiatry, TemertyFaculty of Medicine, University of Toronto, Toronto, ON M5S 1A1 Canada.
James L Kennedy *Centre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.ORCID 0000-0002-8733-3806
Sanjeev Kumar *Centre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.
Krista L Lanctôt *Department of Psychiatry, TemertyFaculty of Medicine, University of Toronto, Toronto, ON M5S 1A1 Canada.ORCID 0000-0001-7024-6637
Linda Mah *Department of Psychiatry, TemertyFaculty of Medicine, University of Toronto, Toronto, ON M5S 1A1 Canada.
Benoit H Mulsant *Centre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.ORCID 0000-0002-0303-6450
Bruce G Pollock *Centre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.ORCID 0000-0003-0802-3998
Aristotle N Voineskos *Centre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.ORCID 0000-0003-0156-0395
Wei Wang *Centre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.
Tarek K RajjiCentre for Addiction and Mental Health, Toronto, ON M6J 1H4 Canada.ORCID 0000-0002-8324-2560
PACt-MD Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Theta-gamma coupling (TGC) is a neurophysiological process that supports working memory. Working memory is associated with other clinical and biological features. The extent to which TGC is associated with these other features and whether it contributes to working memory beyond these features is unknown. Two-hundred-and-three older participants at risk for Alzheimer's dementia-98 with mild cognitive impairment (MCI), 39 with major depressive disorder (MDD) in remission, and 66 with MCI and MDD (MCI + MDD)-completed a clinical assessment, N-back-EEG, and brain MRI. Among them, 190 completed genetic testing, and 121 completed [ Supplementary Information: The online version contains supplementary material available at 10.1007/s11571-023-09938-y.

Indexed as

Alzheimer’s dementiaEEGTheta–gamma couplingWorking memory

Identifiers

PMID38826646
PMCPMC11143125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.