Evidence map›Paper›PMID 38826462›Full record

ArticlebioRxiv : the preprint server for biology2024

Clonal evolution of hematopoietic stem cells after cancer chemotherapy.

Hidetaka Uryu, Koichi Saeki, Hiroshi Haeno, Chiraag Deepak Kapadia, Ken Furudate, Jyoti Nangalia, Michael Spencer Chapman, Li Zhao, Joanne I Hsu, Chong Zhao and 28 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

38 authors.

Hidetaka Uryu
Koichi Saeki
Hiroshi Haeno
Chiraag Deepak Kapadia
Ken Furudate
Jyoti Nangalia
Michael Spencer Chapman
Li Zhao
Joanne I Hsu
Chong Zhao
Shujuan Chen
Tomoyuki Tanaka
Zongrui Li
Hui Yang
Courtney DiNardo
Naval Daver
Naveen Pemmaraju
Nitin Jain
Farhad Ravandi
Jianhua Zhang
Xingzhi Song
Erika Thompson
Hongli Tang
Latasha Little
Curtis Gumbs
Robert Z Orlowski
Muzaffar Qazilbash
Kapil Bhalla
Simona Colla
Hagop Kantarjian
Rashmi Kanagal Shamanna
Carlos Bueso- Ramos
Daisuke Nakada
P Andrew Futreal
Elizabeth Shpall
Margaret Goodell
Guillermo Garcia-Manero

Funding

Project 3: Contribution of inflammation and DNA damaging factors to clonal expansion and malignant transformation in a community cohort of older adultsP01CA265748 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Koichi Takahashi · 2022 to 2026
$13.6M
PPM1D in Clonal Hematopoiesis and MalignanciesR01CA237291 · NCI · BAYLOR COLLEGE OF MEDICINE · PI MARGARET A. GOODELL, Koichi Takahashi · 2019 to 2026
$3.7M
NCI NIH HHS P01 CA265748NCI NIH HHS R01 CA237291
6 · The paper itself

Abstract

Normal hematopoietic stem and progenitor cells (HSPCs) inherently accumulate somatic mutations and lose clonal diversity with age, processes implicated in the development of myeloid malignancies

Identifiers

PMID38826462
PMCPMC11142159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.