Evidence map›Paper›PMID 38826457›Full record

ArticlebioRxiv : the preprint server for biology2024

Identification of Small Molecule Inhibitors of PPM1D Using a Novel Drug Discovery Platform.

Wei Jiang, Subrata Shaw, Jason Rush, Nancy Dumont, John Kim, Ritu Singh, Adam Skepner, Carol Khodier, Cerise Raffier, Ni Yan and 10 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Wei JiangBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Subrata ShawBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Jason RushBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Nancy DumontBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
John KimBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Ritu SinghBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Adam SkepnerBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Carol KhodierBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Cerise RaffierBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Ni YanBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Cameron SchluterBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Xiao YuBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Mateusz SzuchnickiBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Murugappan SathappaBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Josephine KahnDepartment of Medicine, Brigham and Women's Hospital, Boston, MA.
Adam S SperlingBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
David C McKinneyBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Alexandra E GouldBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Colin W GarvieBroad Institute of MIT and Harvard University, Cambridge, MA, USA.
Peter G MillerBroad Institute of MIT and Harvard University, Cambridge, MA, USA.

Funding

Defining mechanisms of thalidomide analog resistanceK08CA252174 · NCI · DANA-FARBER CANCER INST · PI SPERLING, ADAM · 2020 to 2024
$1.3M
NCI NIH HHS K08 CA252174
6 · The paper itself

Abstract

Protein phosphatase, Mg

Identifiers

PMID38826457
PMCPMC11142126

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.