Evidence map›Paper›PMID 38826437›Full record

ArticleResearch square2024

Alzheimer's disease risk allele of

Alena Kozlova, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Stanislau Smirnou, Xiaotong Sun, Kimberly Stephenson, Xiaojie Zhao, Brendan Jamison, Moorthi Ponnusamy and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Alena KozlovaCenter for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.
Siwei ZhangCenter for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.
Ari SudwartsByrd Alzheimer's Center and Research Institute, University of South Florida, Tampa, FL 33613, USA.
Hanwen ZhangCenter for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.ORCID 0000-0001-8490-918X
Stanislau SmirnouByrd Alzheimer's Center and Research Institute, University of South Florida, Tampa, FL 33613, USA.
Xiaotong SunDepartment of Human Genetics, The University of Chicago, Chicago, IL 60637, USA.
Kimberly StephensonCenter for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.
Xiaojie ZhaoCenter for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.
Brendan JamisonCenter for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.
Moorthi PonnusamyByrd Alzheimer's Center and Research Institute, University of South Florida, Tampa, FL 33613, USA.
Xin HeDepartment of Human Genetics, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-9011-5212
Zhiping P PangGrossman Institute for Neuroscience, Quantitative Biology and Human Behavior, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-6183-1233
Alan R SandersCenter for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.ORCID 0000-0001-6629-4011
Hugo J BellenDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-5992-5989
Gopal ThinakaranByrd Alzheimer's Center and Research Institute, University of South Florida, Tampa, FL 33613, USA.ORCID 0000-0001-5523-6780
Jubao DuanCenter for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.ORCID 0000-0002-7215-3220

Funding

Systematic Functional Interpretation of Regulatory Variants in SchizophreniaR01MH106575 · NIMH · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI DUAN, JUBAO · 2016 to 2025
$6.1M
Modeling Alzheimer's disease genetic variants in hiPSCR01AG063175 · NIA · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI DUAN, JUBAO, THINAKARAN, GOPAL · 2019 to 2023
$3.7M
Integrating epigenomics with DNA breathing dynamics for human non-coding disease variantsR01MH116281 · NIMH · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI ALEXANDROV, BOIAN STOIANOV, DUAN, JUBAO · 2019 to 2023
$3.0M
Neuronal Vulnerability to Lipid Droplets and Cholesterol in Alzheimer's DiseaseR01AG081374 · NIA · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI Jubao Duan · 2023 to 2026
$2.7M
Microglial function of GWAS risk factor BIN1 in Alzheimer's disease pathogenesis and inflammatory signalingRF1AG079141 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI RANGARAJU, SRIKANT, THINAKARAN, GOPAL · 2022 to 2022
$2.3M
NIA NIH HHS R01 AG063175NIA NIH HHS R01 AG081374NIA NIH HHS RF1 AG079141NIMH NIH HHS R01 MH106575NIMH NIH HHS R01 MH116281
6 · The paper itself

Abstract

Despite genome-wide association studies of late-onset Alzheimer's disease (LOAD) having identified many genetic risk loci

Identifiers

PMID38826437
PMCPMC11142308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.