Evidence map›Paper›PMID 38826332›Full record

ArticlebioRxiv : the preprint server for biology2024

Neuron-level Prediction and Noise can Implement Flexible Reward-Seeking Behavior.

Chenguang Li, Jonah Brenner, Adam Boesky, Sharad Ramanathan, Gabriel Kreiman

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chenguang LiBiophysics Program, Harvard College, Cambridge, MA 02138.ORCID 0000-0003-2884-6414
Jonah BrennerHarvard University, Cambridge, MA 02138.ORCID 0000-0002-0304-520X
Adam BoeskyHarvard College, Cambridge, MA 02138.ORCID 0009-0005-9830-9966
Sharad RamanathanDepartment of Molecular and Cellular Biology, Harvard University Cambridge, MA 02138.ORCID 0000-0001-9445-1248
Gabriel KreimanBoston Children's Hospital, Harvard Medical School, Boston, MA 02115.ORCID 0000-0003-3505-8475

Funding

Neural dynamics underlying spatiotemporal cognitive integrationR01EY026025 · NEI · BOSTON CHILDREN'S HOSPITAL · PI KREIMAN, GABRIEL · 2016 to 2024
$3.7M
Mechanisms of Synaptic Dopamine Signaling in the Control of BehaviorR01NS117908 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RAMANATHAN, SHARAD, RINGSTAD, NIELS · 2020 to 2024
$2.6M
NEI NIH HHS R01 EY026025NINDS NIH HHS R01 NS117908
6 · The paper itself

Abstract

We show that neural networks can implement reward-seeking behavior using only local predictive updates and internal noise. These networks are capable of autonomous interaction with an environment and can switch between explore and exploit behavior, which we show is governed by attractor dynamics. Networks can adapt to changes in their architectures, environments, or motor interfaces without any external control signals. When networks have a choice between different tasks, they can form preferences that depend on patterns of noise and initialization, and we show that these preferences can be biased by network architectures or by changing learning rates. Our algorithm presents a flexible, biologically plausible way of interacting with environments without requiring an explicit environmental reward function, allowing for behavior that is both highly adaptable and autonomous. Code is available at https://github.com/ccli3896/PaN.

Identifiers

PMID38826332
PMCPMC11142161

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.