Evidence map›Paper›PMID 38826313›Full record

ArticlebioRxiv : the preprint server for biology2024

Germline status and micronutrient availability regulate a somatic mitochondrial quality control pathway via short-chain fatty acid metabolism.

James P Held, Nadir H Dbouk, Adrianna M Strozak, Lantana K Grub, Hayeon Ryou, Samantha H Schaffner, Maulik R Patel

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

James P HeldDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, USA.
Nadir H DboukDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, USA.
Adrianna M StrozakDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, USA.
Lantana K GrubDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, USA.
Hayeon RyouDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, USA.
Samantha H SchaffnerDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, USA.
Maulik R PatelDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, USA.ORCID 0000-0003-3749-0122

Funding

ECHO Laboratory Core at Vanderbilt for Integrated Sample Biobanking and ProcessingU24OD035523 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Suman Ranjan Das, NATASHA Bassam HALASA · 2023 to 2026
$32.8M
TRAINING PROGRAM IN ENVIRONMENTAL TOXICOLOGYT32ES007028 · NIEHS · VANDERBILT UNIVERSITY · PI F PETER Guengerich, Fiona Edith Harrison · 1985 to 2026
$15.7M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Mechanisms of mutant mitochondrial genome modulationR35GM145378 · NIGMS · VANDERBILT UNIVERSITY · PI MAULIK R PATEL · 2022 to 2026
$2.4M
Regulation of mitochondrial heteroplasmy dynamicsR01GM123260 · NIGMS · VANDERBILT UNIVERSITY · PI PATEL, MAULIK R · 2017 to 2021
$1.5M
NIEHS NIH HHS T32 ES007028NIGMS NIH HHS R01 GM123260NIGMS NIH HHS R35 GM145378NIH HHS P40 OD010440NIH HHS U24 OD035523
6 · The paper itself

Abstract

Reproductive status, such as pregnancy and menopause in women, profoundly influences metabolism of the body. Mitochondria likely orchestrate many of these metabolic changes. However, the influence of reproductive status on somatic mitochondria and the underlying mechanisms remain largely unexplored. We demonstrate that reproductive signals modulate mitochondria in the

Identifiers

PMID38826313
PMCPMC11142046

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.