Evidence map›Paper›PMID 38826198›Full record

ArticlebioRxiv : the preprint server for biology2025

gRNAde: Geometric Deep Learning for 3D RNA inverse design.

Chaitanya K Joshi, Arian R Jamasb, Ramon Viñas, Charles Harris, Simon V Mathis, Alex Morehead, Rishabh Anand, Pietro Liò

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Chaitanya K JoshiUniversity of Cambridge, UK.ORCID 0000-0003-4722-1815
Arian R JamasbPrescient Design, Genentech, Roche.ORCID 0000-0002-6727-7579
Ramon ViñasEPFL, Switzerland.
Charles HarrisUniversity of Cambridge, UK.
Simon V MathisUniversity of Cambridge, UK.
Alex MoreheadUniversity of Missouri, USA.
Rishabh AnandNational University of Singapore.
Pietro LiòUniversity of Cambridge, UK.ORCID 0000-0002-0540-5053

Funding

Integrated Prediction of Protein Struture at 1D, 2D and 3D LevelsR01GM093123 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI CHENG, JIANLIN · 2010 to 2023
$3.8M
Deep learning methods for automated and accurate reconstruction of protein structures from cryo-EM image dataR01GM146340 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI CHENG, JIANLIN · 2022 to 2025
$1.4M
NIGMS NIH HHS R01 GM093123NIGMS NIH HHS R01 GM146340
6 · The paper itself

Abstract

Computational RNA design tasks are often posed as inverse problems, where sequences are designed based on adopting a single desired secondary structure without considering 3D conformational diversity. We introduce

Identifiers

PMID38826198
PMCPMC11142113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.