Evidence map›Paper›PMID 38826194›Full record

ArticleResearch square2024

Exploiting ChatGPT for Diagnosing Autism-Associated Language Disorders and Identifying Distinct Features.

Chuanbo Hu, Wenqi Li, Mindi Ruan, Xiangxu Yu, Lynn K Paul, Shuo Wang, Xin Li

Abstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Chuanbo HuDepartment of Computer Science, University at Albany, Albany, 12222, NY, USA.
Wenqi LiDepartment of Computer Science, University at Albany, Albany, 12222, NY, USA.
Mindi RuanLane Department of Computer Science and Electrical Engineering, West Virginia University, Morgantown, 26506, WV, USA.
Xiangxu YuDepartment of Radiology, Washington University in St. Louis, St. Louis, 63110, MO, USA.
Lynn K PaulHumanities and Social Sciences, California Institute of Technology, Pasadena, 91125, CA, USA.
Shuo WangDepartment of Radiology, Washington University in St. Louis, St. Louis, 63110, MO, USA.
Xin LiDepartment of Computer Science, University at Albany, Albany, 12222, NY, USA.ORCID 0000-0003-2067-2763

Funding

Model-Based Investigation of Aberrant Neural Face Representation in AutismR01MH129426 · NIMH · WASHINGTON UNIVERSITY · PI Shuo Wang · 2022 to 2026
$1.9M
NIMH NIH HHS R01 MH129426
6 · The paper itself

Abstract

Diagnosing language disorders associated with autism is a complex and nuanced challenge, often hindered by the subjective nature and variability of traditional assessment methods. Traditional diagnostic methods not only require intensive human effort but also often result in delayed interventions due to their lack of speed and specificity. In this study, we explored the application of ChatGPT, a state-of-the-art large language model, to overcome these obstacles by enhancing diagnostic accuracy and profiling specific linguistic features indicative of autism. Leveraging ChatGPT's advanced natural language processing capabilities, this research aims to streamline and refine the diagnostic process. Specifically, we compared ChatGPT's performance with that of conventional supervised learning models, including BERT, a model acclaimed for its effectiveness in various natural language processing tasks. We showed that ChatGPT substantially outperformed these models, achieving over 13% improvement in both accuracy and F1-score in a zero-shot learning configuration. This marked enhancement highlights the model's potential as a superior tool for neurological diagnostics. Additionally, we identified ten distinct features of autism-associated language disorders that vary significantly across different experimental scenarios. These features, which included echolalia, pronoun reversal, and atypical language usage, were crucial for accurately diagnosing ASD and customizing treatment plans. Together, our findings advocate for adopting sophisticated AI tools like ChatGPT in clinical settings to assess and diagnose developmental disorders. Our approach not only promises greater diagnostic precision but also aligns with the goals of personalized medicine, potentially transforming the evaluation landscape for autism and similar neurological conditions.

Indexed as

Autism spectrum disorderChatGPTLanguage deficitsLarge language modelsMachine learning

Identifiers

PMID38826194
PMCPMC11142355

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.