Evidence map›Paper›PMID 38826050›Full record

ArticlePhilosophical transactions. Series A, Mathematical, physical, and engineering sciences2024

Developing the OpenFlexure Microscope towards medical use: technical and social challenges of developing globally accessible hardware for healthcare.

Joe Knapper, Freya Whiteford, Daniel Rosen, William Wadsworth, Julian Stirling, Catherine Mkindi, Joram Mduda, Valerian L Sanga, Paul T Nyakyi, Thomas Hervé Mboa Nkoudou and 5 more

Abstract read
In one paragraph

Article in Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Open, reproducible hardware for microscopy.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Joe KnapperUniversity of Glasgow , Glasgow, UK.ORCID 0000-0002-5519-1700
Freya WhitefordUniversity of Glasgow , Glasgow, UK.ORCID 0009-0001-8324-1242
Daniel RosenBaylor College of Medicine , Houston, Texas, USA.
William WadsworthDepartment of Physics, University of Bath , Bath, UK.
Julian StirlingFoxhill Engineering , Bath, UK.ORCID 0000-0002-8270-9237
Catherine MkindiIfakara Health Institute , Ifakara, Tanzania.
Joram MdudaIfakara Health Institute , Ifakara, Tanzania.
Valerian L SangaBongo Tech and Research Labs , Dar es Salaam, Tanzania.
Paul T NyakyiBongo Tech and Research Labs , Dar es Salaam, Tanzania.
Thomas Hervé Mboa NkoudouMboalab and African Higher Institute of Open Science and Hardware (AHIOSH) , Yaounde, Cameroon.
Elisée JafsiaMboalab and African Higher Institute of Open Science and Hardware (AHIOSH) , Yaounde, Cameroon.
Stephane FadankaMboalab and African Higher Institute of Open Science and Hardware (AHIOSH) , Yaounde, Cameroon.
Kelsey HummelMD Anderson Cancer Centre , Houston, Texas, USA.ORCID 0000-0002-4499-5316
Sharmila AnandasabapathyBaylor College of Medicine , Houston, Texas, USA.
Richard BowmanUniversity of Glasgow , Glasgow, UK.ORCID 0000-0002-1531-8199

Funding

Royal Society RGF\EA\181034
6 · The paper itself

Abstract

The OpenFlexure Microscope is an accessible, three-dimensional-printed robotic microscope, with sufficient image quality to resolve diagnostic features including parasites and cancerous cells. As access to lab-grade microscopes is a major challenge in global healthcare, the OpenFlexure Microscope has been developed to be manufactured, maintained and used in remote environments, supporting point-of-care diagnosis. The steps taken in transforming the hardware and software from an academic prototype towards an accepted medical device include addressing technical and social challenges, and are key for any innovation targeting improved effectiveness in low-resource healthcare. This article is part of the Theo Murphy meeting issue 'Open, reproducible hardware for microscopy'.

Indexed as

MicroscopyDelivery of Health CareEquipment DesignHumansPoint-of-Care SystemsPrinting, Three-DimensionalRoboticsSoftwareglobal healthmicroscopyopen sourcepathology

Identifiers

PMID38826050
PMCPMC11448745

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.