ArticleImmunology1985
Activation of alveolar macrophages following infection with the parasitic nematode Nippostrongylus brasiliensis.
Article in Immunology, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Modulation of B-cell proliferative response by a soluble extract of Nippostrongylus brasiliensis.Infection and immunity · 2000Article
- Pattern of proinflammatory cytokine mRNA expression during Trichinella spiralis infection of the rat.Infection and immunity · 1996Article
- Tumour necrosis factor, IL-1 and IL-6 in bronchoalveolar washings and their in vitro production during Nippostrongylus brasiliensis infection.Clinical and experimental immunology · 1992Article
- A role for protein kinase C in the production of free oxygen radicals in response to Nippostrongylus brasiliensis.Parasitology research · 1991Article
- The acute-phase protein response in parasite infection. Nippostrongylus brasiliensis and Trichinella spiralis in the rat.Immunology · 1990Article
- The role of free oxygen radicals in the expulsion of primary infections of Nippostrongylus brasiliensis.Parasitology research · 1989Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alveolar macrophages (AM) of rats infected with 3000 Nippostrongylus brasiliensis infective larvae for 2, 8 or 32 days (D2, D8 or D32 AM) quantitatively surpassed AM from uninfected rats in one or more of IgG- or C3-dependent phagocytosis indices, beta-D-glucuronidase release, or spontaneous release of thymocyte activating factor (interleukin-1, IL-1) and hepatocyte stimulation factor (HSF). These observations suggest that N. brasiliensis infection results in the activation of AM. We have reported previously that a greater proportion of AM from infected rats expressed C3 receptors and were helminthocidal in vitro in the presence of complement than normal AM which were not helminthocidal. The acquisition of the activated state by AM during infection may play a role in vivo lung resistance against migrating helminth parasites.
Indexed as
Identifiers
3882558PMC1453519What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.