Evidence map›Paper›PMID 38825505›Full record

ArticleJournal of atherosclerosis and thrombosis2024

Bathing-Related Ischemic Stroke: Association between Stroke Subtype and Cerebral Small Vessel Disease.

Takahiro Ishikawa, Takeo Sato, Motohiro Okumura, Tatsushi Kokubu, Junichiro Takahashi, Tomomichi Kitagawa, Maki Tanabe, Hiroki Takatsu, Asako Onda, Teppei Komatsu and 5 more

Abstract read
In one paragraph

Article in Journal of atherosclerosis and thrombosis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Takahiro IshikawaThe Jikei University School of Medicine.
Takeo SatoDepartment of Neurology, The Jikei University School of Medicine.
Motohiro OkumuraDepartment of Neurology, The Jikei University School of Medicine.
Tatsushi KokubuDepartment of Neurology, The Jikei University School of Medicine.
Junichiro TakahashiDepartment of Neurology, The Jikei University School of Medicine.
Tomomichi KitagawaDepartment of Neurology, The Jikei University School of Medicine.
Maki TanabeDepartment of Neurology, The Jikei University School of Medicine.
Hiroki TakatsuDepartment of Neurology, The Jikei University School of Medicine.
Asako OndaDepartment of Neurology, The Jikei University School of Medicine.
Teppei KomatsuDepartment of Neurology, The Jikei University School of Medicine.
Kenichi SakutaDepartment of Neurology, The Jikei University School of Medicine.
Kenichiro SakaiDepartment of Neurology, The Jikei University School of Medicine.
Tadashi UmeharaDepartment of Neurology, The Jikei University School of Medicine.
Hidetaka MitsumuraDepartment of Neurology, The Jikei University School of Medicine.
Yasuyuki IguchiDepartment of Neurology, The Jikei University School of Medicine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsBathing-related ischemic stroke (BIS) is sometimes fatal. However, its mechanisms and risk factors remain unclear. We aimed to identify the incidence of stroke subtypes in BIS, and clarify the impact of cerebral small vessel disease (CSVD) on BIS.

methodsConsecutive patients with ischemic stroke between October 2012 and February 2022 were retrospectively screened. The inclusion criteria were: 1) onset-to-door time within 7 days; and 2) availability of the results of MRI evaluation of CSVD markers during hospitalization. BIS was defined as an ischemic stroke that occurred while or shortly after bathing. We investigated the incidence of the stroke subtype and the correlation between CSVD markers and BIS.

results1,753 ischemic stroke patients (1,241 [71%] male, median age 69 years) were included. 57 patients (3%) were included in the BIS group. A higher frequency of large artery atherosclerosis (LAA) (prevalence ratio [PR] 2.069, 95% confidence interval [CI] 1.089 to 3.931, p=0.026) and lower frequency of cardio-embolism (CES) (PR 0.362, 95% CI 0.132 to 0.991, p=0.048) in BIS cases were identified. Moreover, lower periventricular hyperintensity (PVH) Fazekas grade (PR 0.671, 95% CI 0.472 to 0.956, p=0.027) and fewer cerebral microbleeds (CMBs) in deep brain region (PR 0.810, 95%CI 0.657 to 0.999, p=0.049) were associated with BIS cases.

conclusionsThe BIS group was more likely to develop LAA and less likely to develop CES. Lower PVH grade and fewer CMBs in deep brain region were associated with the development of BIS.

Indexed as

BathsCerebral Small Vessel DiseasesIschemic StrokeAgedFemaleFollow-Up StudiesHumansIncidenceMagnetic Resonance ImagingMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsAcute ischemic strokeAutonomic nervousBathingCerebral small vessel diseaseLarge artery atherosclerosis

Identifiers

PMID38825505
PMCPMC11620830

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.