Evidence map›Paper›PMID 38824598›Full record

ArticleParasites & vectors2024

Nilgai antelope display no signs of infection upon experimental challenge with a virulent Babesia bovis strain.

Tammi L Johnson, Kelly A Persinger, Naomi S Taus, Sara K Davis, Karen C Poh, Lowell S Kappmeyer, Jacob M Laughery, Janaína Capelli-Peixoto, Kimberly H Lohmeyer, Massaro W Ueti and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasites & vectors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Reproductive Capabilities of Female Nilgai (Animals : an open access journal from MDPI · 2024
    Article
  3. Assessment ofFrontiers in cellular and infection microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tammi L JohnsonTexas A&M AgriLife Research, Uvalde, TX, 78801, USA. tammi.johnson@ag.tamu.edu.
Kelly A PersingerTexas A&M AgriLife Research, Uvalde, TX, 78801, USA.
Naomi S TausUSDA-ARS, Animal Disease Research Unit, Washington State University, Pullman, WA, 99164, USA.
Sara K DavisUSDA-ARS, Animal Disease Research Unit, Washington State University, Pullman, WA, 99164, USA.
Karen C PohUSDA-ARS, Animal Disease Research Unit, Washington State University, Pullman, WA, 99164, USA.
Lowell S KappmeyerUSDA-ARS, Animal Disease Research Unit, Washington State University, Pullman, WA, 99164, USA.
Jacob M LaugheryDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164, USA.
Janaína Capelli-PeixotoDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164, USA.
Kimberly H LohmeyerLivestock Arthropod Pests Research Unit, Knipling-Bushland United States Livestock Insects Research Laboratory, USDA-ARS, Kerrville, TX, 78028, USA.
Massaro W UetiUSDA-ARS, Animal Disease Research Unit, Washington State University, Pullman, WA, 99164, USA.
Pia U OlafsonLivestock Arthropod Pests Research Unit, Knipling-Bushland United States Livestock Insects Research Laboratory, USDA-ARS, Kerrville, TX, 78028, USA.

Funding

USDA-ARS Cooperative Agreement 58-3091-9-014USDA National Institute for Food and Agriculture Hatch Project 1019784
6 · The paper itself

Abstract

backgroundBovine babesiosis is caused by infection with the protozoal parasite Babesia bovis, which is transmitted by Rhipicephalus (Boophilus) spp. It can cause mortality rates up to 90% in immunologically naive Bos taurus cattle. In south Texas, R. (B.) microplus is known to infest nilgai antelope (Boselaphus tragocamelus); however, their susceptibility to infection with B. bovis and their role in the transmission of the parasite remain unknown. In this study, we challenged nilgai antelope with B. bovis and evaluated their susceptibility to infection.

methodsNilgai were needle inoculated with ≈10

resultsNilgai did not display clinical signs of infection upon inoculation with either the merozoite or sporozoite stage of B. bovis. All nilgai were PCR-negative for the parasite, and they did not develop antibodies to B. bovis. No evidence of infection was detected in histological sections of nilgai tissues, and in vitro culture analysis indicated that the nilgai RBCs were not colonized by B. bovis merozoites. Cattle subinoculated with blood from challenged nilgai did not display clinical signs of infection, and they were PCR-negative up to 45 days after transfer.

conclusionsNilgai do not appear to be susceptible to infection with a strain of B. bovis that is lethal to cattle. Tick control on these alternative hosts remains a critical priority, especially given their potential to disseminate ticks over long distances.

Indexed as

AntelopesBabesia bovisBabesiosisAnimalsCattleCattle DiseasesErythrocytesFemalePolymerase Chain ReactionRhipicephalusTexasVirulenceBabesia bovisBoselaphus tragocamelusBovine babesiosisRhipicephalus (Boophilus) microplusWildlife host

Identifiers

PMID38824598
PMCPMC11144341

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.