Evidence map›Paper›PMID 38824590›Full record

ArticleBMC genomics2024

Effects of cold acclimation on serum biochemical parameters and metabolite profiles in Schizothorax prenanti.

Aiyu Wang, Run Zhang, Xianshu Zhang, Chunjie Chen, Quan Gong, Linjie Wang, Yan Wang

Abstract read
In one paragraph

Article in BMC genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Evaluation of Overwintering Performance of Threeline Grunt (Animals : an open access journal from MDPI · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aiyu WangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Run ZhangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Xianshu ZhangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Chunjie ChenCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Quan GongFisheries Institute, Sichuan Academy of Agricultural Sciences, Chengdu, Sichuan, 611713, P.R. China.
Linjie WangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Yan WangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China. wangyan8108@sicau.edu.cn.

Funding

Sichuan Science and Technology Program 22NSFSC3463
6 · The paper itself

Abstract

backgroundEnvironmental temperature is critical in regulating biological functions in fish. S. prenanti is a kind of cold-water fish, but of which we have little knowledge about the metabolic adaptation and physiological responses to long-term cold acclimation.

resultsIn this study, we determined the physiological responses of S. prenanti serum after 30 days of exposure to 6℃. Compared with the control group, the levels of TC, TG, and LDL-C in the serum were significantly (P < 0.05) increased, and the level of glucose was significantly (P < 0.05) decreased under cold acclimation. Cold acclimation had no effect on the gene expression of pro-inflammatory factors and anti-inflammatory factors of S. prenanti. Metabolomics analysis by LC-MS showed that a total of 60 differential expressed metabolites were identified after cold acclimation, which involved in biosynthesis of amino acids, biosynthesis of unsaturated fatty acids, steroid degradation, purine metabolism, and citrate cycle pathways.

conclusionThe results indicate that cold acclimation can alter serum metabolites and metabolic pathways to alter energy metabolism and provide insights for the physiological regulation of cold-water fish in response to cold acclimation.

Indexed as

AcclimatizationCold TemperatureCyprinidaeMetabolomeMetabolomicsAnimalsAmino acidsCold acclimationMetabolomicsSchizothorax prenantiUnsaturated fatty acids

Identifiers

PMID38824590
PMCPMC11143564

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.