Evidence map›Paper›PMID 38824569›Full record

ArticleBMC pregnancy and childbirth2024

Patterns of oxytocin use for induction and augmentation of labour among healthcare providers in Nigeria.

Chioma S Ejekam, Ifeoma P Okafor, Kehinde S Okunade, Uchenna Igbokwe, Jude Nwokike

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Article in BMC pregnancy and childbirth, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Chioma S EjekamAdvanced Centre of Excellence of Drug Research, Herbal Medicine Development and Regulatory Science (ACEDHARS), University of Lagos, Akoka, Lagos, Nigeria. Chioma.s.ejekam@gmail.com.
Ifeoma P OkaforDepartment of Community Health and Primary Care, College of Medicine, University of Lagos, Idiaraba Lagos, Nigeria.
Kehinde S OkunadeDepartment of Obstetrics and Gynaecology, College of Medicine, University of Lagos, Idiaraba Lagos, Nigeria.
Uchenna IgbokweSolina Centre for International Development and Research, Libreville Street, Wuse II, Abuja, Nigeria.
Jude NwokikePromoting the Quality of Medicines Program Plus, U.S Pharmacopeia, Twinbrook Rockville, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe practice of intrapartum use of oxytocin for induction and augmentation of labour is increasing worldwide with documented wide variations in clinical use, especially dose administrations. There is also evidence of intrapartum use by unauthorized cadre of staff.

aimThis study assessed the patterns - frequency of intrapartum use of oxytocin, the doses and routes of administration for induction and augmentation of labour, and identified the predictors of oxytocin use for induction and augmentation of labour by healthcare providers in Nigeria.

methodsThis was a cross-sectional study conducted among healthcare providers - doctors, nurses/midwives and community health workers (CHWs) in public and private healthcare facilities across the country's six geopolitical zones. A multistage sampling technique was used to select 6,299 eligible healthcare providers who use oxytocin for pregnant women during labour and delivery. A self-administered questionnaire was used to collect relevant data and analysed using STATA 17 statistical software. Summary and inferential statistics were done and further analyses using multivariable regression models were performed to ascertain independent predictor variables of correct patterns of intrapartum oxytocin usage. The p-value was set at < 0.05.

resultsOf the 6299 respondents who participated in the study, 1179 (18.7%), 3362 (53.4%), and 1758 (27.9%) were doctors, nurses/midwives and CHWs, respectively. Among the respondents, 4200 (66.7%) use oxytocin for augmentation of labour while 3314 (52.6%) use it for induction of labour. Of the 1758 CHWs, 37.8% and 49% use oxytocin for induction and augmentation of labour, respectively. About 10% of the respondents who use oxytocin for the induction or augmentation of labour incorrectly use the intramuscular route of administration and about 8% incorrectly use intravenous push. Being a doctor, and a healthcare provider from government health facilities were independent positive predictors of the administration of correct dose oxytocin for induction and augmentation of labour. The CHWs were most likely to use the wrong route and dose administration of oxytocin for the induction and augmentation of labour.

conclusionOur study unveiled a concerning clinical practice of intrapartum oxytocin use by healthcare providers in Nigeria - prevalence of intrapartum use of oxytocin, inappropriate routes of administration for induction and augmentation of labour, varied and inappropriately high start dose of administration including unauthorized and high intrapartum use of oxytocin among CHWs.

Indexed as

Health PersonnelLabor, InducedOxytocicsOxytocinAdultCross-Sectional StudiesFemaleHumansLabor, ObstetricMaleNigeriaPractice Patterns, Physicians'PregnancySurveys and QuestionnairesYoung AdultOxytocicsOxytocinAugmentation of labourHealthcare providersInduction of labourIntrapartum oxytocin useNigeriaPatterns of oxytocin use

Identifiers

PMID38824569
PMCPMC11144308

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.