Evidence map›Paper›PMID 38824466›Full record

ReviewThe protein journal2024

Recent Advancements in Biosensors for the Detection and Characterization of Amyloids: A Review.

Md Harun Rashid, Priyankar Sen

Abstract readReview
PubMed Publisher
In one paragraph

Review in The protein journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Md Harun RashidCentre for Bio Separation Technology (CBST), Technology Tower, Vellore Institute of Technology, VIT University, Vellore, 632014, Tamil Nadu, India.ORCID http://orcid.org/0000-0003-3126-0107
Priyankar SenCentre for Bio Separation Technology (CBST), Technology Tower, Vellore Institute of Technology, VIT University, Vellore, 632014, Tamil Nadu, India. priyankar.sen@vit.ac.in.ORCID http://orcid.org/0000-0003-4729-7297

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern medicine has increased the human lifespan. However, with an increase in average lifespan risk of amyloidosis increases. Amyloidosis is a condition characterized by protein misfolding and aggregation. Early detection of amyloidosis is crucial, yet conventional diagnostic methods are costly and lack precision, necessitating innovative tools. This review explores recent advancements in diverse amyloid detection methodologies, highlighting the need for interdisciplinary research to develop a miniaturized electrochemical biosensor leveraging nanotechnology. However, the diagnostics industry faces obstacles such as skilled labor shortages, standardized selection processes, and concurrent multi-analyte identification challenges. Research efforts are focused on integrating electrochemical techniques into clinical applications and diagnostics, with the successful transition of miniaturized technologies from development to testing posing a significant hurdle. Label-free transduction techniques like voltammetry and electrochemical impedance spectroscopy (EIS) have gained traction due to their rapid, cost-effective, and user-friendly nature.

Indexed as

AmyloidBiosensing TechniquesAmyloidosisDielectric SpectroscopyElectrochemical TechniquesHumansAmyloidAlzheimer’s DiseaseAmyloidosisAβELISANanoparticles

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.