Evidence map›Paper›PMID 38824246›Full record

SynthesisScientific reports2024

Diagnostic value of combined ultrasound contrast and elastography for differentiating benign and malignant thyroid nodules: a meta-analysis.

Funing Liu, Yihan Wang, Yu Xiong, Xin Li, Jun Yao, Hao Ju, Fu Ren, Luwei Zhang, Hongbo Wang

Abstract readMeta-Analysis
In one paragraph

Synthesis in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Funing LiuSchool of First Clinical College, Shenyang Medical College, Shenyang, People's Republic of China.
Yihan WangSchool of Public Health, Shenyang Medical College, Shenyang, People's Republic of China.
Yu XiongSchool of First Clinical College, Shenyang Medical College, Shenyang, People's Republic of China.
Xin LiSchool of Stomatology, Shenyang Medical College, Shenyang, People's Republic of China.
Jun YaoSchool of Forensic Medicine, China Medical University, Shenyang, People's Republic of China.
Hao JuShengjing Hospital of China Medical University, Shenyang, People's Republic of China.
Fu RenDepartment of Human Anatomy, School of Basic Medicine, Shenyang Medical College, Shenyang, People's Republic of China.
Luwei Zhang242 Hospital of Shenyang Medical College, Shenyang, People's Republic of China. 2907311795@qq.com.
Hongbo WangDepartment of Human Anatomy, School of Basic Medicine, Shenyang Medical College, Shenyang, People's Republic of China. wanghongbo@symc.edu.cn.

Funding

Center Guiding Local Science and Technology Foundation of Liaoning Science and Technology Committee 2023JH6/100100021Technology Department of Liaoning Province No. 2023JH2/101300079
6 · The paper itself

Abstract

The diagnostic value of contrast-enhanced ultrasound combined with ultrasound elastography for benign and malignant thyroid nodules is still controversial, so we used meta-analysis to seek controversial answers. The PubMed, OVID, and CNKI databases were searched according to the inclusion and exclusion criteria. The literature was selected from the establishment of each database to February 2024. The QUADAS-2 tool assessed diagnostic test accuracy. SROC curves and Spearman's correlation coefficient were made by Review Manager 5.4 software to assess the presence of threshold effects in the literature. Meta-Disc1.4 software was used for Cochrane-Q and χ

Indexed as

Contrast MediaElasticity Imaging TechniquesThyroid NoduleUltrasonographyDiagnosis, DifferentialHumansSensitivity and SpecificityThyroid NeoplasmsContrast MediaContrast-enhanced ultrasoundMeta-analysisThyroid nodulesUltrasonic elastography

Identifiers

PMID38824246
PMCPMC11144246

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.