Evidence map›Paper›PMID 38824241›Full record

ArticleMolecular biology reports2024

Differential expression of circRNAs during osteogenic/odontogenic differentiation of stem cells from apical papilla promoted by blue light-emitting diode.

Jiaxin Li, Shifen Wang, Yajiao Ren, Hao Li, Yan Zhou, Xiaorong Lan, Yao Wang

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Article in Molecular biology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiaxin LiSchool of Stomatology, Southwest Medical University, Luzhou, 646000, China.
Shifen WangSchool of Stomatology, Southwest Medical University, Luzhou, 646000, China.
Yajiao RenSchool of Stomatology, Southwest Medical University, Luzhou, 646000, China.
Hao LiSchool of Stomatology, Southwest Medical University, Luzhou, 646000, China.
Yan ZhouSchool of Stomatology, Southwest Medical University, Luzhou, 646000, China.
Xiaorong LanLuzhou Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Southwest Medical University, Luzhou, 646000, China.
Yao WangSchool of Stomatology, Southwest Medical University, Luzhou, 646000, China. 438730587@qq.com.ORCID http://orcid.org/0000-0001-8400-1665

Funding

the Medical Research Project of Sichuan Province S21015the Science and Technology Project of Luzhou 2023SYF127the Scientific Project of Southwest Medical University 2021ZKMS013
6 · The paper itself

Abstract

backgroundCircular RNA (circRNA) is a key player in regulating the multidirectional differentiation of stem cells. Previous research by our group found that the blue light-emitting diode (LED) had a promoting effect on the osteogenic/odontogenic differentiation of human stem cells from apical papilla (SCAPs). This research aimed to investigate the differential expression of circRNAs during the osteogenic/odontogenic differentiation of SCAPs regulated by blue LED. MATERIALS AND

methodsSCAPs were divided into the irradiation group (4 J/cm

resultsIt showed 301 circRNAs were differentially expressed. GO and KEGG analyses suggested that these circRNAs were associated with some signaling pathways related to osteogenic/odontogenic differentiation. And the circRNA-miRNA-mRNA networks were also successfully constructed.

conclusionCircRNAs were involved in the osteogenic/odontogenic differentiation of SCAPs promoted by blue LED. In this biological process, circRNA-miRNA-mRNA networks served an important purpose, and circRNAs regulated this process through certain signaling pathways.

Indexed as

Cell DifferentiationDental PapillaLightOdontogenesisOsteogenesisRNA, CircularStem CellsBlue LightCells, CulturedGene Expression ProfilingGene Expression RegulationGene OntologyGene Regulatory NetworksHigh-Throughput Nucleotide SequencingHumansMicroRNAsMicroRNAsRNA, CircularRNA, MessengerCircular RNAGene expressionHuman stem cells from apical papillaLEDOsteogenic/odontogenic differentiation

Identifiers

PMID38824241

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.