Evidence map›Paper›PMID 38823347›Full record

Trial reportAddictive behaviors2024

The prospective relationship between a-priori intentions for and patterns of e-cigarette use among adults who smoke cigarettes.

Riley A O'Neal, Matthew J Carpenter, Amy E Wahlquist, Eleanor L S Leavens, Tracy T Smith, Margaret C Fahey

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Addictive behaviors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2026
    Pooled it
  2. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  3. Trial
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Riley A O'NealArnold School of Public Health, University of South Carolina, United States.
Matthew J CarpenterDepartment of Psychiatry & Behavioral Sciences, Medical University of South Carolina (MUSC), United States; Department of Public Health Sciences, MUSC, United States; Hollings Cancer Center, MUSC, United States.
Amy E WahlquistCenter for Rural Health Research, East Tennessee State University, United States.
Eleanor L S LeavensDepartment of Population Health, The University of Kansas School of Medicine, United States; The University of Kansas Comprehensive Cancer Center, United States.
Tracy T SmithDepartment of Psychiatry & Behavioral Sciences, Medical University of South Carolina (MUSC), United States; Hollings Cancer Center, MUSC, United States.
Margaret C FaheyDepartment of Psychiatry & Behavioral Sciences, Medical University of South Carolina (MUSC), United States. Electronic address: faheym@musc.edu.

Funding

DRUG ABUSE TRAINING PROGRAMT32DA007288 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Christopher W Cowan, Rachel Penrod-Martin · 1991 to 2026
$11.8M
A Naturalistic Nationwide Randomized Study of e-Cigarette Uptake and ConsequencesR01CA210625 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI CARPENTER, MATTHEW J · 2017 to 2021
$2.6M
Impact of e-cigarette characteristics on reinforcement and tobacco use patterns among current smokersK01DA047433 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SMITH, TRACY TAYLOR · 2019 to 2023
$988k
NCI NIH HHS R01 CA210625NIDA NIH HHS K01 DA047433NIDA NIH HHS T32 DA007288
6 · The paper itself

Abstract

backgroundElectronic (e-)cigarettes may help adult cigarette smokers achieve cigarette cessation, depending on patterns of e-cigarette use. Among cigarette smokers who do not use e-cigarettes, it is unclear if and how a-priori intentions for use are related to uptake patterns. Longitudinal studies have focused on established e-cigarette users or adolescent and young adult populations exclusively.

methodsWithin a nationwide randomized clinical trial (N = 638), adult cigarette smokers not currently using e-cigarettes were randomized (2:1) to receive (or not) one-month sampling of e-cigarettes. An exploratory factor analysis (EFA) was performed on an established 15-item measure assessing a-priori intentions for e-cigarette use to identify latent variables. Among those receiving e-cigarette products, regression models examined relationships between intentions and: 1) uptake (yes/no), 2) frequency (number of days per week), and 3) amount (puffing episodes per day) of e-cigarette use at one-month follow-up.

resultsTwo factors emerged from the EFA: 1) cigarette-related intentions (e.g., cigarette cessation, no smell) and 2) novel appeal of e-cigarettes (e.g., flavors). Three items remained and were treated as separate intentions: "feels like cigarette smoking", "curiosity", and "affordability". In the final multivariable models, "feel like cigarette smoking" predicted more frequent e-cigarette use (β = 0.187, SE = 0.086, p = 0.03); however, none of the five factors/intentions were significantly associated with uptake or amount of use.

conclusionsFor adult cigarette smokers not currently using e-cigarettes, a-priori intentions for using e-cigarettes might not be predictive of if or how these products will be used in the future, suggesting that motives may not drive use behavior.

Indexed as

Cigarette SmokingElectronic Nicotine Delivery SystemsIntentionVapingAdolescentAdultFactor Analysis, StatisticalFemaleHumansMaleMiddle AgedProspective StudiesSmoking CessationYoung AdultCigarette smokingE-cigarette intentionsE-cigarette use

Identifiers

PMID38823347
PMCPMC11589789

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.