Evidence map›Paper›PMID 38822978›Full record

Trial reportCancer causes & control : CCC2024

The effect of mailed outreach on FIT completion among patients aged 45-50 in a safety net healthcare system.

Sean P McClellan, Tanya Khan, Henry Rafferty, Jonathan Wong, Sylvia La, Shreya Patel, Ma Somsouk

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Cancer causes & control : CCC, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Positive Predictive Value of Symptoms for Early-Onset Colorectal Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sean P McClellanDepartment of Family and Community Medicine, University of California, San Francisco, CA, USA. smccle2@uic.edu.
Tanya KhanDivision of Gastroenterology, University of California, San Francisco, CA, USA.
Henry RaffertySan Francisco Health Network, San Francisco, CA, USA.
Jonathan WongSan Francisco Health Network, San Francisco, CA, USA.
Sylvia LaSan Francisco Health Network, San Francisco, CA, USA.
Shreya PatelDivision of Gastroenterology, University of California, San Francisco, CA, USA.
Ma SomsoukDivision of Gastroenterology, University of California, San Francisco, CA, USA.

Funding

HRSA T32 HP 19025
6 · The paper itself

Abstract

purposeColorectal cancer screening is recommended starting at age 45, but there has been little research on strategies to promote screening in patients younger than 50.

methodsAn outreach program quasi-randomly assigned patients aged 45-50 without recent fecal immunochemical test (FIT), colonoscopy or contraindications to screening to two intervention arms: electronic outreach with email and text (electronic outreach only) versus electronic outreach plus mailed outreach with FIT, an instructional letter and a prepaid return envelope (mailed + electronic outreach). In response to known disparities in screening uptake, all Black patients were assigned to receive mailed + electronic outreach.

resultsAmong patients quasi-randomly assigned to an intervention (non-Black patients), the 180-day FIT completion rate was 18.8% in the electronic outreach only group (n = 1,318) and 25.0% in the mailed + electronic outreach group (n = 1,364) (difference 6.2% [95% CI 3.0, 9.4]). FIT completion was 16.6% among Black patients (n = 469), 8.4% (95% CI 4.1, 12.6) lower than among non-Black patients also assigned to mailed + electronic outreach.

conclusionAmong patients aged 45-50, mailed + electronic outreach had a greater effect on FIT completion than electronic outreach alone. Crossover between intervention groups likely lead to an underestimation of the effect of mailed outreach.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerElectronic MailFemaleHumansMaleMass ScreeningMiddle AgedOccult BloodPostal ServiceSafety-net ProvidersColorectal neoplasmsDiagnosisEarly detection of cancerHumansMethodsMiddle agedSafety-net providers

Identifiers

PMID38822978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.