Evidence map›Paper›PMID 38822755›Full record

ArticleJCO clinical cancer informatics2024

Characterizing the Increase in Artificial Intelligence Content Detection in Oncology Scientific Abstracts From 2021 to 2023.

Frederick M Howard, Anran Li, Mark F Riffon, Elizabeth Garrett-Mayer, Alexander T Pearson

Abstract read
In one paragraph

Article in JCO clinical cancer informatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Blinded by the Bot: Benchmarking GPT and Gemini Against Human Authors in Otolaryngology Reviews.World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
  4. Article
  5. Article
  6. [How to detect scientific texts generated with artificial intelligence?]Revista medica del Instituto Mexicano del Seguro Social · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Can ChatGPT pass the Turkish Orthopedics and Traumatology Board Examination? Turkish orthopedic surgeons versus artificial intelligence.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025
    Observational
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Frederick M HowardSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.ORCID 0000-0002-6039-1141
Anran LiSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Mark F RiffonCenter for Research and Analytics, American Society of Clinical Oncology, Alexandria, VA.
Elizabeth Garrett-MayerCenter for Research and Analytics, American Society of Clinical Oncology, Alexandria, VA.ORCID 0000-0003-4709-0333
Alexander T PearsonSection of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.ORCID 0000-0003-2801-7456

Funding

The Funding Mechanism of the Pilot TrialR01CA276652 · NCI · UNIVERSITY OF CHICAGO · PI Hiroyuki Abe, Gregory S. Karczmar · 2023 to 2026
$5.0M
Integrating Clinical, Pathologic, and Immune Features to Predict Breast Cancer Recurrence and Chemotherapy BenefitK08CA283261 · NCI · UNIVERSITY OF CHICAGO · PI Frederick Matthew Howard · 2023 to 2026
$806k
Deep learning for oral premalignancy evaluationR56DE030958 · NIDCR · UNIVERSITY OF CHICAGO · PI PEARSON, ALEXANDER THOMAS · 2021 to 2021
$331k
NCI NIH HHS K08 CA283261NCI NIH HHS R01 CA276652NIDCR NIH HHS R56 DE030958
6 · The paper itself

Abstract

purposeArtificial intelligence (AI) models can generate scientific abstracts that are difficult to distinguish from the work of human authors. The use of AI in scientific writing and performance of AI detection tools are poorly characterized.

methodsWe extracted text from published scientific abstracts from the ASCO 2021-2023 Annual Meetings. Likelihood of AI content was evaluated by three detectors: GPTZero, Originality.ai, and Sapling. Optimal thresholds for AI content detection were selected using 100 abstracts from before 2020 as negative controls, and 100 produced by OpenAI's GPT-3 and GPT-4 models as positive controls. Logistic regression was used to evaluate the association of predicted AI content with submission year and abstract characteristics, and adjusted odds ratios (aORs) were computed.

resultsFifteen thousand five hundred and fifty-three abstracts met inclusion criteria. Across detectors, abstracts submitted in 2023 were significantly more likely to contain AI content than those in 2021 (aOR range from 1.79 with Originality to 2.37 with Sapling). Online-only publication and lack of clinical trial number were consistently associated with AI content. With optimal thresholds, 99.5%, 96%, and 97% of GPT-3/4-generated abstracts were identified by GPTZero, Originality, and Sapling respectively, and no sampled abstracts from before 2020 were classified as AI generated by the GPTZero and Originality detectors. Correlation between detectors was low to moderate, with Spearman correlation coefficient ranging from 0.14 for Originality and Sapling to 0.47 for Sapling and GPTZero.

conclusionThere is an increasing signal of AI content in ASCO abstracts, coinciding with the growing popularity of generative AI models.

Indexed as

Abstracting and IndexingArtificial IntelligenceMedical OncologyHumans

Identifiers

PMID38822755
PMCPMC11371107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.