Evidence map›Paper›PMID 38822149›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2024

Respiratory outcomes of neonates born after previable premature rupture of membranes and treated with gentle ventilation.

Sinead Brady, Mary Martin, Divya Keerthy, Grace Liao, Noelle Breslin, Elvira Parravicini

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sinead BradyDivision of Neonatal and Perinatal Medicine, Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY, USA. Sb4028@cumc.columbia.edu.ORCID 0000-0001-9395-8100
Mary MartinColumbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.
Divya KeerthyDivision of Neonatology, Department of Pediatrics New York Presbyterian Hospital Queens, New York, NY, USA.ORCID 0009-0002-6308-470X
Grace LiaoDivision of Neonatology, Department of Pediatrics, Zucker School of Medicine at Hofstra University, New Hyde Park, NY, USA.
Noelle BreslinDivision of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University Vagelos College of Physicians and Surgeons and Columbia University Irving Medical Center, New York, NY, USA.
Elvira ParraviciniDivision of Neonatal and Perinatal Medicine, Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aim to describe neonatal respiratory outcomes following previable preterm premature rupture of membranes(PPROM) when gentle ventilation is utilized. We also report maternal morbidity and mortality. STUDY

designThis is a retrospective single-center cohort study of infants delivered between 2016 and 2020 that included infants born at ≥23 weeks without major congenital anomaly after a pregnancy complicated with PPROM before 23 weeks gestation. Statistical analysis utilized unpaired Student's t-test or Mann-Whitney U-test when appropriate.

results35 infants from 33 pregnancies were included. 91.4% of infants survived until discharge and 12.1% developed Bronchopulmonary Dysplasia (BPD). Those who developed BPD had significantly lower amniotic fluid levels prior to delivery (p < 0.05). There was no significant maternal morbidity or mortality in this cohort.

conclusionThis cohort had high survival and low rates of respiratory morbidities. This suggests the use of gentle ventilation might be the optimal strategy for patients born after previable PPROM.

Indexed as

Bronchopulmonary DysplasiaPremature Rupture of Fetal MembranesAdultFemaleGestational AgeHumansInfant, NewbornInfant, PrematureMalePregnancyRespiration, ArtificialRetrospective Studies

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.