Evidence map›Paper›PMID 38821927›Full record

ArticleNature communications2024

Atomistic mechanism of coupling between cytosolic sensor domain and selectivity filter in TREK K2P channels.

Berke Türkaydin, Marcus Schewe, Elena Barbara Riel, Friederike Schulz, Johann Biedermann, Thomas Baukrowitz, Han Sun

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Structure-Function Relationships of KAdvances in experimental medicine and biology · 2026
    Review
  4. Review
  5. Article
  6. Gating mechanism of the two-pore-domain potassium channel THIK1.Nature structural & molecular biology · 2025
    Article
  7. Article
  8. Article
  9. Journal of chemical theory and computation · 2025
    Article
  10. Structure of the human TWIK-2 potassium channel and its inhibition by pimozide.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Berke Türkaydin *Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.ORCID http://orcid.org/0000-0003-1699-0312
Marcus Schewe *Institute of Physiology, Kiel University, Kiel, Germany. m.schewe@physiologie.uni-kiel.de.ORCID http://orcid.org/0000-0002-6192-5651
Elena Barbara RielInstitute of Physiology, Kiel University, Kiel, Germany.ORCID http://orcid.org/0000-0003-3227-9344
Friederike SchulzInstitute of Physiology, Kiel University, Kiel, Germany.ORCID http://orcid.org/0000-0002-1525-9256
Johann BiedermannLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.ORCID http://orcid.org/0000-0002-7542-1999
Thomas BaukrowitzInstitute of Physiology, Kiel University, Kiel, Germany. t.baukrowitz@physiologie.uni-kiel.de.ORCID http://orcid.org/0000-0003-4562-0505
Han SunLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany. hsun@fmp-berlin.de.ORCID http://orcid.org/0000-0002-1655-0838

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) EXC 2008/1-390540038Deutsche Forschungsgemeinschaft (German Research Foundation) RU2518
6 · The paper itself

Abstract

The two-pore domain potassium (K

Indexed as

Ion Channel GatingMolecular Dynamics SimulationPotassium Channels, Tandem Pore DomainAnimalsCrystallography, X-RayCytosolHEK293 CellsHumansPhosphorylationProtein DomainsKCNK10 protein, humanpotassium channel protein TREK-1Potassium Channels, Tandem Pore Domain

Identifiers

PMID38821927
PMCPMC11143257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.