ArticleBrain stimulation
TMS provokes target-dependent intracranial rhythms across human cortical and subcortical sites.
Article in Brain stimulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A meta-analysis suggests that TMS targeting the hippocampal network selectively improves episodic memory.eLife · 2026Pooled it
- Mechanisms of transcranial magnetic brain stimulation.Physiological reviews · 2026Review
- Clinical utility and prospective of TMS-EEG: Updated review from an international expert group.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Review
- Transcranial magnetic stimulation to the dorsolateral prefrontal cortex modulates single-neuron activity in humans.bioRxiv : the preprint server for biology · 2026Article
- Multimodal evidence for hippocampal engagement and modulation by functional connectivity-guided parietal TMS.Nature communications · 2026Article
- Investigating the effects of TMS-related somatosensory inputs on TMS-evoked potentials provides evidence against significant interaction.Scientific reports · 2026Article
- A practical preprocessing pipeline for concurrent TMS-iEEG: Critical steps and methodological considerations.NeuroImage · 2026Article
- Noninvasive profiling of input-output excitability curves in human prefrontal cortex.bioRxiv : the preprint server for biology · 2025Article
- Advances in transcranial magnetic stimulation for psychological symptom management in Parkinson's disease.World journal of psychiatry · 2025Review
- A Practical Preprocessing Pipeline for Concurrent TMS-iEEG: Critical Steps and Methodological Considerations.bioRxiv : the preprint server for biology · 2025Article
- Neuromodulation with Ultrasound: Hypotheses on the Directionality of Effects and Community Resource.medRxiv : the preprint server for health sciences · 2025Article
- Dorsolateral prefrontal cortex TMS evokes responses in the subgenual anterior cingulate cortex: Evidence from human intracranial EEG.bioRxiv : the preprint server for biology · 2024Article
- A Comprehensive Overview of the Current Status and Advancements in Various Treatment Strategies against Epilepsy.ACS pharmacology & translational science · 2024Review
- Networks through the lens of high-frequency oscillations.Frontiers in network physiology · 2024Review
- Article
- Dorsolateral prefrontal cortex TMS evokes responses in the subgenual anterior cingulate cortex: Intracranial EEG evidence from two human cases.Brain stimulationArticle
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Abstract
backgroundTranscranial magnetic stimulation (TMS) is believed to alter ongoing neural activity and cause circuit-level changes in brain function. While the electrophysiological effects of TMS have been extensively studied with scalp electroencephalography (EEG), this approach generally evaluates low-frequency neural activity at the cortical surface. However, TMS can be safely used in patients with intracranial electrodes (iEEG), allowing for direct assessment of deeper and more localized oscillatory responses across the frequency spectrum. OBJECTIVE/HYPOTHESIS: Our study used iEEG to understand the effects of TMS on human neural activity in the spectral domain. We asked (1) which brain regions respond to cortically-targeted TMS, and in what frequency bands, (2) whether deeper brain structures exhibit oscillatory responses, and (3) whether the neural responses to TMS reflect evoked versus induced oscillations.
methodsWe recruited 17 neurosurgical patients with indwelling electrodes and recorded neural activity while patients underwent repeated trials of single-pulse TMS at either the dorsolateral prefrontal cortex (DLPFC) or parietal cortex. iEEG signals were analyzed using spectral methods to understand the oscillatory responses to TMS.
resultsStimulation to DLPFC drove widespread low-frequency increases (3-8 Hz) in frontolimbic cortices and high-frequency decreases (30-110 Hz) in frontotemporal areas, including the hippocampus. Stimulation to parietal cortex specifically provoked low-frequency responses in the medial temporal lobe. While most low-frequency activity was consistent with phase-locked evoked responses, anterior frontal regions exhibited induced theta oscillations following DLPFC stimulation.
conclusionsBy combining TMS with intracranial EEG recordings, our results suggest that TMS is an effective means to perturb oscillatory neural activity in brain-wide networks, including deeper structures not directly accessed by stimulation itself.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.