Evidence map›Paper›PMID 38821100›Full record

ReviewThe Lancet. Oncology2024

Production and regulatory issues for theranostics.

Francesco Giammarile, Diana Paez, Richard Zimmermann, Cathy S Cutler, Amirreza Jalilian, Aruna Korde, Peter Knoll, Nayyereh Ayati, Jason S Lewis, Suzanne E Lapi and 7 more

Abstract readReview
In one paragraph

Review in The Lancet. Oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Assessing Value for Money in Theranostic Nuclear Medicine: A Systematic Review.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Pooled it
  2. Article
  3. Review
  4. Adsorption treatment ofAnnals of nuclear medicine · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Clinical Applications of Theranostics.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  10. Future of radiotheranostics.BMJ oncology · 2026
    Review
  11. Challenges and Opportunities in Radioligand Therapy.Journal of nuclear medicine technology · 2025
    Review
  12. Review
  13. NeoadjuvantCancers · 2025
    Review
  14. Theranostics in nuclear medicine: the era of precision oncology.Medical oncology (Northwood, London, England) · 2025
    Review
  15. Review
  16. Review
  17. ARTnet Perspectives and Contributions to Theranostics.World journal of nuclear medicine · 2025
    Review
  18. Theranostics Implementation: Opportunities and Challenges.World journal of nuclear medicine · 2025
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Francesco GiammarileDivision of Human Health, Department of Nuclear Safety and Security, International Atomic Energy Agency, Vienna, Austria.
Diana PaezDivision of Human Health, Department of Nuclear Safety and Security, International Atomic Energy Agency, Vienna, Austria.
Richard ZimmermannChrysalium Consulting, Lalaye, France; MEDraysintell, Louvain la Neuve, Belgium; Oncidium Foundation, Auderghem, Belgium.
Cathy S CutlerIsotope Research and Production Department, Brookhaven National Laboratory Upton, New York City, NY, USA.
Amirreza JalilianDivision of Physical and Chemical Sciences, Department of Nuclear Safety and Security, International Atomic Energy Agency, Vienna, Austria.
Aruna KordeDivision of Physical and Chemical Sciences, Department of Nuclear Safety and Security, International Atomic Energy Agency, Vienna, Austria.
Peter KnollDivision of Physical and Chemical Sciences, Department of Nuclear Safety and Security, International Atomic Energy Agency, Vienna, Austria.
Nayyereh AyatiCentre for Health Economics, Monash Business School, Monash University, Melbourne, VIC, Australia.
Jason S LewisDepartment of Radiology and Program in Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, Upton, NY, USA; Departments of Radiology and Pharmacology, Weill Cornell Medical College, New York City, NY, USA.
Suzanne E LapiDepartments of Radiology and Chemistry, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Roberto C Delgado BoltonDepartment of Diagnostic Imaging (Radiology) and Nuclear Medicine, University Hospital San Pedro and Centre for Biomedical Research of La Rioja, Logroño, Spain; Servico Cántabro de Salud, Santander, Spain.
Jolanta KunikowskaNuclear Medicine Department, Medical University of Warsaw, Warsaw, Poland.
Enrique Estrada LobatoDivision of Human Health, Department of Nuclear Safety and Security, International Atomic Energy Agency, Vienna, Austria.
Jean-Luc UrbainRoswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Ola HolmbergDepartment of Nuclear Science and Applications, and Division of Radiation, Transport and Waste Safety, Department of Nuclear Safety and Security, International Atomic Energy Agency, Vienna, Austria.
May Abdel-WahabDivision of Human Health, Department of Nuclear Safety and Security, International Atomic Energy Agency, Vienna, Austria.
Andrew M ScottDepartment of Molecular Imaging and Therapy, Austin Health, Melbourne, VIC, Australia; Department of Molecular Imaging and Therapy, Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia; Faculty of Medicine, University of Melbourne, Melbourne, VIC, Australia. Electronic address: andrew.scott@onjcri.org.au.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Leveraging Pb-203/212 for the Theranostic Imaging and Therapy of Prostate CancerR35CA232130 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI LEWIS, JASON S. · 2019 to 2025
$8.2M
NCI NIH HHS P30 CA008748NCI NIH HHS R35 CA232130
6 · The paper itself

Abstract

Theranostics has become a major area of innovation and progress in cancer care over the last decade. In view of the introduction of approved therapeutics in neuroendocrine tumours and prostate cancer in the last 10 years, the ability to provide access to these treatments has emerged as a key factor in ensuring global benefits from this cancer therapy approach. In this Series paper we explore the issues that affect access to and availability of theranostic radiopharmaceuticals, including supply and regulatory issues that might affect the availability of theranostic treatments for patients with cancer.

Indexed as

RadiopharmaceuticalsTheranostic NanomedicineHumansNeoplasmsPrecision MedicineRadiopharmaceuticals

Identifiers

PMID38821100
PMCPMC11325260

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.