Evidence map›Paper›PMID 38821099›Full record

ReviewThe Lancet. Oncology2024

Trends in nuclear medicine and the radiopharmaceutical sciences in oncology: workforce challenges and training in the age of theranostics.

Andrew M Scott, Brian M Zeglis, Suzanne E Lapi, Peter J H Scott, Albert D Windhorst, May Abdel-Wahab, Francesco Giammarile, Diana Piaez, Amirreza Jalilian, Peter Knoll and 8 more

Erratum issuedAbstract readReview
In one paragraph

Review in The Lancet. Oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Assessing Value for Money in Theranostic Nuclear Medicine: A Systematic Review.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Pooled it
  2. Article
  3. Article
  4. Soft skills for medical physicists: Evolving a profession.Journal of applied clinical medical physics · 2026
    Article
  5. Article
  6. Combination therapy strategies in engineeredCell communication and signaling : CCS · 2026
    Review
  7. Future of radiotheranostics.BMJ oncology · 2026
    Review
  8. Clinical Applications of Theranostics.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Theranostics in nuclear medicine: the era of precision oncology.Medical oncology (Northwood, London, England) · 2025
    Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Theranostics Implementation: Opportunities and Challenges.World journal of nuclear medicine · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Andrew M ScottDepartment of Molecular Imaging and Therapy, Austin Health, Melbourne, VIC, Australia; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia; Faculty of Medicine, University of Melbourne, Melbourne, VIC, Australia.
Brian M ZeglisDepartment of Chemistry, Hunter College, City University of New York, New York, NY, USA; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Radiology, Weill Cornell Medical College, New York, NY, USA.
Suzanne E LapiDepartment of Radiology and Department of Chemistry, O'Neal Comprehensive Cancer Center at UAB, University of Alabama at Birmingham, Birmingham, AL, USA.
Peter J H ScottDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA.
Albert D WindhorstDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, Netherlands; Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
May Abdel-WahabDivision of Human Health, International Atomic Energy Agency, Vienna, Austria.
Francesco GiammarileNuclear Medicine and Diagnostic Imaging Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.
Diana PiaezNuclear Medicine and Diagnostic Imaging Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.
Amirreza JalilianDepartment of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.
Peter KnollDivision of Human Health, International Atomic Energy Agency, Vienna, Austria.
Aruna KordeDivision of Physical and Chemical Sciences, International Atomic Energy Agency, Vienna, Austria.
Shrikant VichareNuclear Medicine and Diagnostic Imaging Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.
Nayyereh AyatiCentre for Health Economics, Monash Business School, Monash University, Melbourne, VIC, Australia.
Sze Ting LeeDepartment of Molecular Imaging and Therapy, Austin Health, Melbourne, VIC, Australia; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia; Faculty of Medicine, University of Melbourne, Melbourne, VIC, Australia; Department of Surgery, University of Melbourne, Melbourne, VIC, Australia; School of Health and Biomedical Science, RMIT University, Melbourne, VIC, Australia.
Serge K LyashchenkoDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Radiology, Weill Cornell Medical College, New York, NY, USA.
Jingjing ZhangDepartment of Diagnostic Radiology, National University of Singapore, Singapore; Clinical Imaging Research Centre, Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Jean Luc UrbainDepartment of Diagnostic Imaging (Radiology and Nuclear Medicine), Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Jason S LewisDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Program in Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Radiology, Weill Cornell Medical College, New York, NY, USA; Department of Pharmacology, Weill Cornell Medical College, New York, NY, USA. Electronic address: lewisj2@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Leveraging Pb-203/212 for the Theranostic Imaging and Therapy of Prostate CancerR35CA232130 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI LEWIS, JASON S. · 2019 to 2025
$8.2M
Synthesis of Novel PET Radiotracers for Imaging in Alzheimer’s Disease and Related DisordersR01EB021155 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SANFORD, MELANIE S., SCOTT, PETER JAMES HENRY · 2016 to 2024
$3.2M
NCI NIH HHS P30 CA008748NCI NIH HHS R35 CA232130NIBIB NIH HHS R01 EB021155
6 · The paper itself

Abstract

Although the promise of radionuclides for the diagnosis and treatment of disease was recognised soon after the discovery of radioactivity in the late 19th century, the systematic use of radionuclides in medicine only gradually increased over the subsequent hundred years. The past two decades, however, has seen a remarkable surge in the clinical application of diagnostic and therapeutic radiopharmaceuticals, particularly in oncology. This development is an exciting time for the use of theranostics in oncology, but the rapid growth of this area of nuclear medicine has created challenges as well. In particular, the infrastructure for the manufacturing and distribution of radiopharmaceuticals remains in development, and regulatory bodies are still optimising guidelines for this new class of drug. One issue of paramount importance for achieving equitable access to theranostics is building a sufficiently trained workforce in high-income, middle-income, and low-income countries. Here, we discuss the key challenges and opportunities that face the field as it seeks to build its workforce for the 21st century.

Indexed as

Medical OncologyNuclear MedicineRadiopharmaceuticalsHealth WorkforceHumansNeoplasmsRadiopharmaceuticals

Identifiers

PMID38821099
PMCPMC11345887

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.