Evidence map›Paper›PMID 38821010›Full record

ArticleAddictive behaviors2024

A preliminary investigation of physical and mental health features of cannabis & nicotine co-use among adolescents and young adults by sex.

Alexander L Wallace, Kelly E Courtney, Natasha E Wade, Neal Doran, Everett L Delfel, Rachel Baca, Laura E Hatz, Courtney Thompson, Gianna Andrade, Joanna Jacobus

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Addictive behaviors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alexander L WallaceUniversity of California San Diego, Psychiatry Department, La Jolla, CA 92093, USA.
Kelly E CourtneyUniversity of California San Diego, Psychiatry Department, La Jolla, CA 92093, USA.
Natasha E WadeUniversity of California San Diego, Psychiatry Department, La Jolla, CA 92093, USA.
Neal DoranUniversity of California San Diego, Psychiatry Department, La Jolla, CA 92093, USA; Psychology Service, VA San Diego Healthcare System, San Diego, CA 92161, USA.
Everett L DelfelUniversity of California San Diego, Psychiatry Department, La Jolla, CA 92093, USA; SDSU / UC San Diego Joint Doctoral Program in Clinical Psychology, USA.
Rachel BacaUniversity of California San Diego, Psychiatry Department, La Jolla, CA 92093, USA.
Laura E HatzUniversity of California San Diego, Psychiatry Department, La Jolla, CA 92093, USA.
Courtney ThompsonUniversity of California San Diego, Psychiatry Department, La Jolla, CA 92093, USA.
Gianna AndradeUniversity of California San Diego, Psychiatry Department, La Jolla, CA 92093, USA.
Joanna JacobusUniversity of California San Diego, Psychiatry Department, La Jolla, CA 92093, USA. Electronic address: jjacobus@health.ucsd.edu.

Funding

ABCD-USA Consortium: Research ProjectU01DA041089 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joanna Jacobus, Susan F. Tapert · 2015 to 2026
$31.7M
Alcohol Research in the Science/Practitioner ModelT32AA013525 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY, ANDREA SPADONI TOWNSEND · 2002 to 2026
$8.4M
Cannabis and Nicotine Co-Use Influences on Protracted Development of Neural Structure and FunctionR01DA054106 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joanna Jacobus · 2021 to 2026
$3.2M
Vaping in Childhood and Adolescence: Cognitive and Behavioral ConsequencesR01DA054980 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Neal Doran, Joanna Jacobus · 2022 to 2026
$1.4M
Effects of Comorbid Cannabis and Tobacco Product Use on Adolescent NeurodevelopmentR21DA047953 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JACOBUS, JOANNA · 2019 to 2020
$433k
NIAAA NIH HHS T32 AA013525NIDA NIH HHS R01 DA054106NIDA NIH HHS R01 DA054980NIDA NIH HHS R21 DA047953NIDA NIH HHS U01 DA041089
6 · The paper itself

Abstract

introductionCannabis and nicotine/tobacco products (NTP) are commonly co-used in adolescence and young adulthood; however, limited research has been done on predictive health behaviors to co-use. The current study is a preliminary investigation into the relationships of modifiable health behaviors on cannabis and NTP co-use in adolescents and young adults.

method221 participants (ages 16-22) were characterized into cannabis use only (N = 55), NTP use only (N = 20), cannabis and NTP co-use (used cannabis and NTP; N = 96) and control (no use; N = 50) groups based on past 30-day use. Self-report measures for physical activity, sleep quality, mental health, and reward responsivity were utilized. Participants were given a comprehensive neurocognitive battery. Logistic regressions of self-report measures and fluid intelligence composite scores on substance use group status were run stratified by sex.

resultsHigher approach reward sensitivity traits were associated with increased likelihood of cannabis use only (Odds Ratio (OR) = 1.15, p = .036) in female participants. Increased aerobic activity was associated with decreased likelihood of cannabis use only (OR = 0.91, p = .047) and cannabis and NTP co-use (OR = 0.88, p = .007) in female participants. Higher anxiety was associated with increased likelihood of cannabis NTP co-use (OR = 1.51, p = 0.025) in male participants. DISCUSSION: Several health behaviors were linked with cannabis use and cannabis and NTP co-use in both females and male adolescents and young adults. Health markers differed by sex suggesting differing mechanisms of substance co-use. This study informs targetable health behaviors for prevention and intervention efforts.

Indexed as

ExerciseAdolescentAnxietyFemaleHealth BehaviorHumansMaleMarijuana SmokingMarijuana UseMental HealthRewardSex FactorsSleep QualityYoung AdultAdolescentsExerciseMental healthSubstance useYoung adults

Identifiers

PMID38821010
PMCPMC11703446

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.