Evidence map›Paper›PMID 38820984›Full record

ArticleRedox biology2024

Microenvironment-triggered cascade metal-polyphenolic nanozyme for ROS/NO synergistic hyperglycemic wound healing.

Shuo Shi, Yaru Han, Jianxing Feng, Jingru Shi, Xiaoling Liu, Bangfeng Fu, Jianlong Wang, Wentao Zhang, Jinyou Duan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Redox biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shuo ShiShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, Shaanxi, China; College of Food Science and Engineering, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Yaru HanCollege of Food Science and Engineering, Northwest A&F University, Yangling, 712100, Shaanxi, China; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA.
Jianxing FengCollege of Food Science and Engineering, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Jingru ShiShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Xiaoling LiuDepartment of Mechanical Engineering, Columbia University, New York, NY, 10027, USA.
Bangfeng FuCollege of Food Science and Engineering, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Jianlong WangCollege of Food Science and Engineering, Northwest A&F University, Yangling, 712100, Shaanxi, China. Electronic address: wanglong79@nwsuaf.edu.cn.
Wentao ZhangCollege of Food Science and Engineering, Northwest A&F University, Yangling, 712100, Shaanxi, China. Electronic address: zhangwt@nwsuaf.edu.cn.
Jinyou DuanShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, Shaanxi, China. Electronic address: jduan@nwsuaf.edu.cn.

Funding

Macau Young Scholars Program AM2022021National Postdoctoral Program for Innovative Talents ( BX20180263 )National Science Foundation of China 31901794
6 · The paper itself

Abstract

Wound infection of hyperglycemic patient often has extended healing period and increased probability due to the high glucose level. However, achieving precise and safe therapy of the hyperglycemic wound with specific wound microenvironment (WME) remains a major challenge. Herein, a WME-activated smart L-Arg/GOx@TA-Fe (LGTF) nanozymatic system composed of generally recognized as safe (GRAS) compound is engineered. The nanozymatic system combining metal-polyphenol nanozyme (tannic acid-Fe

Indexed as

Glucose OxidaseHyperglycemiaNitric OxideReactive Oxygen SpeciesWound HealingAnimalsAnti-Bacterial AgentsGlucoseHumansMiceRatsAnti-Bacterial AgentsGlucoseGlucose OxidaseNitric OxideReactive Oxygen SpeciesAntibacterialGas therapyHyperglycemic wound healingNanozymeROS

Identifiers

PMID38820984
PMCPMC11177078

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.