Evidence map›Paper›PMID 38820932›Full record

ArticleUltrasonics sonochemistry2024

Macrophages-mediated delivery of protoporphyrin for sonodynamic therapy of rheumatoid arthritis.

Lin Wu, Kai Zhao, Leyuan Xu, Junming Cui, Li Ruan, Shifang Bei, Jin Cao, Xueyong Qi, Song Shen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ultrasonics sonochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Iron metabolism in rheumatic diseases.Journal of translational autoimmunity · 2025
    Review
  4. Stimuli-Responsive Nanoplatforms for Precision Intervention in Rheumatoid Arthritis.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lin WuAffiliated Hospital of Jiangsu University, Zhenjiang 212001, China.
Kai ZhaoAffiliated Hospital of Jiangsu University, Zhenjiang 212001, China; College of Pharmaceutical Sciences, Jiangsu University, Zhenjiang, Jiangsu 212013, China.
Leyuan XuCollege of Pharmaceutical Sciences, Jiangsu University, Zhenjiang, Jiangsu 212013, China.
Junming CuiAffiliated Hospital of Jiangsu University, Zhenjiang 212001, China; College of Pharmaceutical Sciences, Jiangsu University, Zhenjiang, Jiangsu 212013, China.
Li RuanAffiliated Hospital of Jiangsu University, Zhenjiang 212001, China; College of Pharmaceutical Sciences, Jiangsu University, Zhenjiang, Jiangsu 212013, China.
Shifang BeiAffiliated People's Hospital of Jiangsu University, Zhenjiang 212002, China. Electronic address: 93318756@qq.com.
Jin CaoCollege of Pharmaceutical Sciences, Jiangsu University, Zhenjiang, Jiangsu 212013, China.
Xueyong QiCollege of Pharmaceutical Sciences, Jiangsu University, Zhenjiang, Jiangsu 212013, China.
Song ShenCollege of Pharmaceutical Sciences, Jiangsu University, Zhenjiang, Jiangsu 212013, China. Electronic address: jsdx.shensong@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease characterized by infiltration of inflammatory cells, hyperplasia of synovium, and destruction of the joint cartilage. Owing to the low drug delivery efficiency and limited immunosuppression effect, complete cure for RA remains a formidable challenge. Here, we show that live macrophages (Mφs) carrying protoporphyrin-loaded Fe

Indexed as

Arthritis, RheumatoidMacrophagesProtoporphyrinsUltrasonic TherapyAnimalsCytokinesHumansMagnetite NanoparticlesMiceRAW 264.7 CellsCytokinesMagnetite NanoparticlesProtoporphyrinsIron oxide nanoparticlesMacrophagesRheumatoid arthritisSonodynamic therapyTargeting delivery

Identifiers

PMID38820932
PMCPMC11179255

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.