Evidence map›Paper›PMID 38820421›Full record

Trial reportPloS one2024

The impact of oxytocin on emotion recognition and trust: Does disordered eating moderate these relationships?

Isabel Krug, Stephanie Fung, Shanshan Liu, Janet Treasure, Chia Huang, Kim Felmingham, Matthew Fuller-Tyszkiewicz, Olivia McConchie

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Isabel KrugMelbourne School of Psychological Sciences, The University of Melbourne, Melbourne, VIC, Australia.ORCID 0000-0002-5275-3595
Stephanie FungMelbourne School of Psychological Sciences, The University of Melbourne, Melbourne, VIC, Australia.
Shanshan LiuMelbourne School of Psychological Sciences, The University of Melbourne, Melbourne, VIC, Australia.
Janet TreasureDepartment of Psychological Medicine, King's College London, Institute of Psychiatry and Neuroscience, Section of Eating Disorders, London, United Kingdom.
Chia HuangEating Disorders Program, The Melbourne Clinic, Richmond, Victoria, Australia.
Kim FelminghamMelbourne School of Psychological Sciences, The University of Melbourne, Melbourne, VIC, Australia.
Matthew Fuller-TyszkiewiczSchool of Psychology, Deakin University, Geelong, VIC, Australia.
Olivia McConchieMelbourne School of Psychological Sciences, The University of Melbourne, Melbourne, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe current study aimed to investigate the impact of oxytocin on emotion recognition, trust, body image, affect, and anxiety and whether eating disorder (ED) symptoms moderated any of these relationships.

methodParticipants (n = 149) were female university students, who were randomly allocated to receive in a double-blind nature, a single dose of oxytocin intranasal spray (n = 76) or a placebo (saline) intranasal spray (n = 73). Participants were asked to complete an experimental measure of emotion recognition and an investor task aimed to assess trust.

resultsThe oxytocin group exhibited better overall performance on the emotion recognition task (especially with recognising positive emotions), and a decline in state positive affect than the control group at post-intervention. However, these effects were not moderated by ED symptom severity, nor were effects found for state anxiety, negative affect, body image and recognising negative emotions in the emotion recognition task.

conclusionThe current findings contribute to the growing literature on oxytocin, emotion recognition and positive affect and suggest that ED pathology does not moderate these relationships. Future research would benefit from examining the efficacy of an oxytocin intervention using a within-subjects, cross-over design, in those with sub-clinical and clinical EDs, as well as healthy controls.

Indexed as

Administration, IntranasalEmotionsFeeding and Eating DisordersOxytocinTrustAdolescentAdultAnxietyBody ImageDouble-Blind MethodFemaleHumansRecognition, PsychologyYoung AdultOxytocin

Identifiers

PMID38820421
PMCPMC11142561

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.