Evidence map›Paper›PMID 38820163›Full record

ArticleScience advances2024

Pf bacteriophages hinder sputum antibiotic diffusion via electrostatic binding.

Qingquan Chen, Pam Cai, Tony Hong Wei Chang, Elizabeth Burgener, Michael J Kratochvil, Aditi Gupta, Aviv Hargil, Patrick R Secor, Josefine Eilsø Nielsen, Annelise E Barron and 4 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Phage-Mediated Iron Acquisition bybioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. bioRxiv : the preprint server for biology · 2025
    Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Qingquan Chen *Division of Infectious Diseases and Geographic Medicine, Dept. of Medicine, Stanford University School of Medicine, Beckman Center, 279 Campus Drive, Stanford, CA 94305, USA.ORCID 0000-0002-6849-177X
Pam Cai *Department of Chemical Engineering, Stanford University, Stanford, CA, 94305, USA.ORCID 0000-0002-0838-0402
Tony Hong Wei ChangDivision of Infectious Diseases and Geographic Medicine, Dept. of Medicine, Stanford University School of Medicine, Beckman Center, 279 Campus Drive, Stanford, CA 94305, USA.ORCID 0000-0003-4227-6163
Elizabeth BurgenerCenter for Excellence in Pulmonary Biology, Department of Pediatrics, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0001-8969-6232
Michael J KratochvilDivision of Infectious Diseases and Geographic Medicine, Dept. of Medicine, Stanford University School of Medicine, Beckman Center, 279 Campus Drive, Stanford, CA 94305, USA.ORCID 0000-0002-8845-2524
Aditi GuptaDivision of Infectious Diseases and Geographic Medicine, Dept. of Medicine, Stanford University School of Medicine, Beckman Center, 279 Campus Drive, Stanford, CA 94305, USA.ORCID 0009-0001-7188-2536
Aviv HargilDivision of Infectious Diseases and Geographic Medicine, Dept. of Medicine, Stanford University School of Medicine, Beckman Center, 279 Campus Drive, Stanford, CA 94305, USA.ORCID 0009-0007-8121-9301
Patrick R SecorDivision of Biological Sciences, University of Montana, Missoula, MT 59812, USA.ORCID 0000-0001-7123-3037
Josefine Eilsø NielsenDepartment of Bioengineering, School of Medicine & School of Engineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0001-9274-5533
Annelise E BarronDepartment of Bioengineering, School of Medicine & School of Engineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-0735-6873
Carlos MillaCenter for Excellence in Pulmonary Biology, Department of Pediatrics, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0001-5515-3053
Sarah C HeilshornDepartment of Materials Science and Engineering, Stanford University, 476 Lomita Mall, Stanford, CA 94305, USA.ORCID 0000-0002-9801-6304
Andy SpakowitzDepartment of Chemical Engineering, Stanford University, Stanford, CA, 94305, USA.ORCID 0000-0002-0585-1942
Paul L BollykyDivision of Infectious Diseases and Geographic Medicine, Dept. of Medicine, Stanford University School of Medicine, Beckman Center, 279 Campus Drive, Stanford, CA 94305, USA.ORCID 0000-0003-2499-9448

Funding

Immunization against filamentous bacteriophages to prevent bacterial infectionR01AI138981 · NIAID · UNIVERSITY OF MONTANA · PI EVANS, JAY T. · 2018 to 2022
$5.4M
The role of macrophages in chronic suppurative otitis media associated sensory hearing lossR01DC019965 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Peter Luke Santa Maria · 2022 to 2026
$3.6M
Non-invasive Monitoring for Infections and Rejection after Lung TransplantationR01AI182349 · NIAID · STANFORD UNIVERSITY · PI Paul L Bollyky · 2024 to 2026
$1.8M
Pathogenesis of Pf Bacteriophages in Pseudomonas Cystic Fibrosis lung InfectionsR01HL148184 · NHLBI · STANFORD UNIVERSITY · PI MILLA, CARLOS · 2019 to 2022
$1.7M
Studies on bacteriophages in respiratory diseasesK24AI166718 · NIAID · STANFORD UNIVERSITY · PI Paul L Bollyky · 2022 to 2026
$815k
Bacteriophage as a predictive biomarker in chronic Pseudomonas airway diseaseK23HL169902 · NHLBI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI Elizabeth Bendig Burgener · 2023 to 2026
$796k
NHLBI NIH HHS K23 HL169902NHLBI NIH HHS R01 HL148184NIAID NIH HHS K24 AI166718NIAID NIH HHS R01 AI138981NIAID NIH HHS R01 AI182349NIDCD NIH HHS R01 DC019965
6 · The paper itself

Abstract

Despite great progress in the field, chronic

Indexed as

Anti-Bacterial AgentsPseudomonas aeruginosaSputumStatic ElectricityBacteriophagesBiofilmsCystic FibrosisDiffusionHumansPseudomonas InfectionsTobramycinAnti-Bacterial AgentsTobramycin

Identifiers

PMID38820163
PMCPMC11141622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.