Evidence map›Paper›PMID 38819629›Full record

SynthesisCancer medicine2024

Efficiency of transurethral en-bloc resection vs. conventional transurethral resection for non-muscle-invasive bladder cancer: An umbrella review.

Deng-Xiong Li, Qing-Xin Yu, Rui-Cheng Wu, Jie Wang, De-Chao Feng, Shi Deng

Abstract readMeta-AnalysisComparative StudySystematic Review
In one paragraph

Synthesis in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Deng-Xiong LiDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.ORCID 0000-0002-1943-6758
Qing-Xin YuDepartment of pathology, Ningbo Clinical Pathology Diagnosis Center, Ningbo City, Zhejiang Province, China.
Rui-Cheng WuDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Jie WangDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
De-Chao FengDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.ORCID 0000-0002-8267-9920
Shi DengDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEn-Bloc transurethral resection of bladder tumor (ERBT) was clinically used to resect non-muscle-invasive bladder cancer (NMIBC). However, discrepancies persist regarding the comparisons between ERBT and conventional transurethral resection of bladder tumor (cTURBT).

methodsWe conducted a comprehensive search in PubMed, Embase, Web of Science, Cochrane Database of Systematic Reviews, and performed manual searches of reference lists to collect and extract data. Data evaluation was carried out using Review Manager 5.4.0, Rx64 4.1.3, and relevant packages.

resultsThere were nine eligible meta-analyses and nine eligible RCTs in our study. NMIBC patients undergoing ERBT were significant associated with a lower rate of bladder perforation and obturator nerve reflex compared to those receiving cTURBT. Our pooled result indicated that ERBT and cTURBT required similar operation time. Regarding postoperative outcomes, ERBT demonstrated superior performance compared to cTURBT in terms of detrusor muscle presence, catheterization time, and residual tumor. ERBT exhibited a higher rate of three-month recurrence-free survival (RFS) compared to those receiving cTURBT (p < 0.05; I

conclusionUsing a combination of umbrella review and meta-analysis, we demonstrated that ERBT had better or comparable perioperative outcome and improved 3 and 12 month RFS than cTURBT. We suggest that ERBT maybe a better surgical method for patients with NMIBC compared with cTURBT.

Indexed as

CystectomyUrinary Bladder NeoplasmsHumansNeoplasm InvasivenessNon-Muscle Invasive Bladder NeoplasmsTreatment OutcomeUrethrabladder cancerEn bloc resection of bladder tumortransurethral resection of bladder tumorurothelial carcinoma

Identifiers

PMID38819629
PMCPMC11141332

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.