Sclerosing well-differentiated liposarcoma: two diagnostically challenging mimicker cases and a literature review.

Ariella R Noorily, Syed T Hoda, Jose G Mantilla, Mohammad Samim

Abstract readCase ReportsReview

In one paragraph

Review in Skeletal radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ariella R NoorilyDepartment of Radiology, NYU Grossman School of Medicine, 301 East 17th Street, 6th Floor, Radiology, New York, NY, 10003, USA. ariella.noorily@nyulangone.org.ORCID http://orcid.org/0000-0003-1794-3171

Syed T HodaDepartment of Anatomical Pathology, NYU Grossman School of Medicine, New York, USA.

Jose G MantillaDepartment of Anatomical Pathology, NYU Grossman School of Medicine, New York, USA.

Mohammad SamimDepartment of Radiology, NYU Grossman School of Medicine, 301 East 17th Street, 6th Floor, Radiology, New York, NY, 10003, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liposarcoma is a malignant soft tissue tumor with several subtypes, the most common of which is well-differentiated liposarcoma (WDL) or atypical lipomatous tumor (ALT). WDL/ALTs are further divided into three histological subtypes, including lipoma-like, sclerosing, and inflammatory. While the majority of these tumors are predominantly fatty, the sclerosing variant demonstrates diverse histologic and radiographic characteristics, including variable amounts of fibrosis and fat. Because of this histological variability and relative rarity, the sclerosing WDL/ALT can present diagnostic dilemmas. We present two cases of sclerosing WDL/ALT, both of which demonstrated high degrees of fibrosis and a paucity of fat, mimicking desmoid fibromatosis and other fibrotic soft tissue tumors. Thus, it is important for radiologists to be aware of the subtypes of liposarcoma and their unique characteristics, and to consider sclerosing WDL/ALT in cases of fibrotic soft tissue tumors.

Indexed as

LiposarcomaAged, 80 and overDiagnosis, DifferentialHumansMagnetic Resonance ImagingMaleMiddle AgedSclerosisSoft Tissue NeoplasmsTomography, X-Ray ComputedDesmoid fibromatosisImagingSclerosingWell-differentiated liposarcoma

Identifiers

PMID38819449

DOI10.1007/s00256-024-04716-1

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.